Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary research
The ecotoxicity assessment of new substances is crucial for their considered launch on the market. Due to various properties of chemical compounds, however, the application of biotests can be challenging. In the case of insoluble compounds, a proper, non-toxic solvent must be applied. The presented...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2018-01-01
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| Series: | E3S Web of Conferences |
| Online Access: | https://doi.org/10.1051/e3sconf/20184400066 |
| _version_ | 1818439042370371584 |
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| author | Kielka Ewa Siedlecka Agata Wolf Mirela Stróżak Sylwia Piekarska Katarzyna Strub Daniel |
| author_facet | Kielka Ewa Siedlecka Agata Wolf Mirela Stróżak Sylwia Piekarska Katarzyna Strub Daniel |
| author_sort | Kielka Ewa |
| collection | DOAJ |
| description | The ecotoxicity assessment of new substances is crucial for their considered launch on the market. Due to various properties of chemical compounds, however, the application of biotests can be challenging. In the case of insoluble compounds, a proper, non-toxic solvent must be applied. The presented preliminary results demonstrate the extremely high ecotoxicity of camphor and camphor oxime, assessed by means of the Microtox system. A 81.9% Basic Test with 14 dilutions was applied. The ecotoxicity of a solvent (i.e. DMSO) was also assessed. The initial concentration of substances was 5%. EC50 values reached 0.00023% and 0.00007% for camphor and camphor oxime, respectively, after 15 min. of incubation of the samples with bioluminescent bacteria. The ecotoxicity of the solvent remained negligible. Due to the extremely high ecotoxicity values of the tested substances, another range of concentrations needs to be applied in future tests to confirm the results. |
| first_indexed | 2024-12-14T17:50:10Z |
| format | Article |
| id | doaj.art-3793f216732746cdbfe78bbb4682c898 |
| institution | Directory Open Access Journal |
| issn | 2267-1242 |
| language | English |
| last_indexed | 2024-12-14T17:50:10Z |
| publishDate | 2018-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj.art-3793f216732746cdbfe78bbb4682c8982022-12-21T22:52:40ZengEDP SciencesE3S Web of Conferences2267-12422018-01-01440006610.1051/e3sconf/20184400066e3sconf_eko-dok2018_00066Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary researchKielka EwaSiedlecka AgataWolf MirelaStróżak SylwiaPiekarska KatarzynaStrub DanielThe ecotoxicity assessment of new substances is crucial for their considered launch on the market. Due to various properties of chemical compounds, however, the application of biotests can be challenging. In the case of insoluble compounds, a proper, non-toxic solvent must be applied. The presented preliminary results demonstrate the extremely high ecotoxicity of camphor and camphor oxime, assessed by means of the Microtox system. A 81.9% Basic Test with 14 dilutions was applied. The ecotoxicity of a solvent (i.e. DMSO) was also assessed. The initial concentration of substances was 5%. EC50 values reached 0.00023% and 0.00007% for camphor and camphor oxime, respectively, after 15 min. of incubation of the samples with bioluminescent bacteria. The ecotoxicity of the solvent remained negligible. Due to the extremely high ecotoxicity values of the tested substances, another range of concentrations needs to be applied in future tests to confirm the results.https://doi.org/10.1051/e3sconf/20184400066 |
| spellingShingle | Kielka Ewa Siedlecka Agata Wolf Mirela Stróżak Sylwia Piekarska Katarzyna Strub Daniel Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary research E3S Web of Conferences |
| title | Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary research |
| title_full | Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary research |
| title_fullStr | Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary research |
| title_full_unstemmed | Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary research |
| title_short | Ecotoxicity assessment of camphor oxime using Microtox assay – preliminary research |
| title_sort | ecotoxicity assessment of camphor oxime using microtox assay preliminary research |
| url | https://doi.org/10.1051/e3sconf/20184400066 |
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