An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical Hospital

Introduction. Liver transplantation is currently considered to be the only method of radical treatment for adults and children with incurable liver diseases. The most important aspects of liver transplantation are the correct selection of an appropriate recipient and compilation and maintenance of a...

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Main Authors: M. A. Nartailakov, R. R. Abdeev, I. Z. Salimgareev, A. R. Zagitov, R. R. Nuriakhmetov, I. I. Ivanov, K. N. Zolotukhin, I. V. Polyakov, L. I. Bashirova
Format: Article
Language:English
Published: Bashkir State Medical University 2019-03-01
Series:Креативная хирургия и онкология
Subjects:
Online Access:https://www.surgonco.ru/jour/article/view/352
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author M. A. Nartailakov
R. R. Abdeev
I. Z. Salimgareev
A. R. Zagitov
R. R. Nuriakhmetov
I. I. Ivanov
K. N. Zolotukhin
I. V. Polyakov
L. I. Bashirova
author_facet M. A. Nartailakov
R. R. Abdeev
I. Z. Salimgareev
A. R. Zagitov
R. R. Nuriakhmetov
I. I. Ivanov
K. N. Zolotukhin
I. V. Polyakov
L. I. Bashirova
author_sort M. A. Nartailakov
collection DOAJ
description Introduction. Liver transplantation is currently considered to be the only method of radical treatment for adults and children with incurable liver diseases. The most important aspects of liver transplantation are the correct selection of an appropriate recipient and compilation and maintenance of a liver transplant waiting list. This article aims to analyze the structure of the severe chronic liver disease patient population included in the liver transplant waiting list at the G. G. Kuvatov Republican Clinical Hospital (the City of Ufa).Materials and methods. We analyzed the waiting list drawn and maintained over the 2007-2018 period based on the examination of 789 patients with liver cirrhosis of various etiologies.Results and discussion. Out of all the patients with liver cirrhosis of different etiologies (Child-Pugh score classes A, B, and C) 149 (18.8 %) were included in the waiting list. The ages of patients included in the liver transplant waiting list ranged from 19 to 69. The mortality rate amounted to 38.9 % (58 people); of these patients 31 (53.4 %) had hepatic cirrhosis (HC) of autoimmune etiology, 18 (31.0 %) — HC of viral etiology, and 6 (10.3 %) — alveococcosis of the liver. The rate of the waiting list expansion for patients aged 20-29 compared to those aged 0-19 amounted to 1.32 %. Such a dynamics for the 30-39 age group compared to the 20-29 age group was 11.51 %. The number of people aged 40-49 compared to the preceding age group remained the same.Conclusion. Our analysis of the waiting list sets the percentage of patients with autoimmune HC in the population of patients with this disease at 59 %. These patients are characterized by a rapid progression of liver failure and high mortality. The statistical analysis of liver transplant waiting lists facilitate the optimization of procedures used to select and manage such patients, as well as to prevent, in a timely manner, the development of complications thus improving the prognosis of survival.
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spelling doaj.art-3796939a31664c11b18f6eed59494ce02023-03-13T10:01:08ZengBashkir State Medical UniversityКреативная хирургия и онкология2307-05012076-30932019-03-018431031510.24060/2076-3093-2018-8-4-310-315303An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical HospitalM. A. Nartailakov0R. R. Abdeev1I. Z. Salimgareev2A. R. Zagitov3R. R. Nuriakhmetov4I. I. Ivanov5K. N. Zolotukhin6I. V. Polyakov7L. I. Bashirova8Башкирский государственный медицинский университетРеспубликанская клиническая больница им. Г.Г. КуватоваРеспубликанская клиническая больница им. Г.Г. КуватоваБашкирский государственный медицинский университетРеспубликанская клиническая больница им. Г.Г. КуватоваРеспубликанская клиническая больница им. Г.Г. КуватоваРеспубликанская клиническая больница им. Г.Г. КуватоваРеспубликанская клиническая больница им. Г.Г. КуватоваРеспубликанская клиническая больница им. Г.Г. КуватоваIntroduction. Liver transplantation is currently considered to be the only method of radical treatment for adults and children with incurable liver diseases. The most important aspects of liver transplantation are the correct selection of an appropriate recipient and compilation and maintenance of a liver transplant waiting list. This article aims to analyze the structure of the severe chronic liver disease patient population included in the liver transplant waiting list at the G. G. Kuvatov Republican Clinical Hospital (the City of Ufa).Materials and methods. We analyzed the waiting list drawn and maintained over the 2007-2018 period based on the examination of 789 patients with liver cirrhosis of various etiologies.Results and discussion. Out of all the patients with liver cirrhosis of different etiologies (Child-Pugh score classes A, B, and C) 149 (18.8 %) were included in the waiting list. The ages of patients included in the liver transplant waiting list ranged from 19 to 69. The mortality rate amounted to 38.9 % (58 people); of these patients 31 (53.4 %) had hepatic cirrhosis (HC) of autoimmune etiology, 18 (31.0 %) — HC of viral etiology, and 6 (10.3 %) — alveococcosis of the liver. The rate of the waiting list expansion for patients aged 20-29 compared to those aged 0-19 amounted to 1.32 %. Such a dynamics for the 30-39 age group compared to the 20-29 age group was 11.51 %. The number of people aged 40-49 compared to the preceding age group remained the same.Conclusion. Our analysis of the waiting list sets the percentage of patients with autoimmune HC in the population of patients with this disease at 59 %. These patients are characterized by a rapid progression of liver failure and high mortality. The statistical analysis of liver transplant waiting lists facilitate the optimization of procedures used to select and manage such patients, as well as to prevent, in a timely manner, the development of complications thus improving the prognosis of survival.https://www.surgonco.ru/jour/article/view/352печени трансплантациялист ожиданияцирроз печениэхинококкоз печенипеченочная недостаточностьбезрецидивная выживаемостьпрогноз
spellingShingle M. A. Nartailakov
R. R. Abdeev
I. Z. Salimgareev
A. R. Zagitov
R. R. Nuriakhmetov
I. I. Ivanov
K. N. Zolotukhin
I. V. Polyakov
L. I. Bashirova
An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical Hospital
Креативная хирургия и онкология
печени трансплантация
лист ожидания
цирроз печени
эхинококкоз печени
печеночная недостаточность
безрецидивная выживаемость
прогноз
title An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical Hospital
title_full An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical Hospital
title_fullStr An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical Hospital
title_full_unstemmed An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical Hospital
title_short An Analysis of the Liver Transplant Waiting List at the G. G. Kuvatov Republican Clinical Hospital
title_sort analysis of the liver transplant waiting list at the g g kuvatov republican clinical hospital
topic печени трансплантация
лист ожидания
цирроз печени
эхинококкоз печени
печеночная недостаточность
безрецидивная выживаемость
прогноз
url https://www.surgonco.ru/jour/article/view/352
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