Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin
The authors realize longitudinal deep-brain imaging through an intact mouse skull by constructing a high-speed reflection matrix microscope at 1.3 µm wavelength and developing a computational conjugate adaptive optics algorithm eliminating skull aberrations.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35738-9 |
| _version_ | 1797958544053501952 |
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| author | Yongwoo Kwon Jin Hee Hong Sungsam Kang Hojun Lee Yonghyeon Jo Ki Hean Kim Seokchan Yoon Wonshik Choi |
| author_facet | Yongwoo Kwon Jin Hee Hong Sungsam Kang Hojun Lee Yonghyeon Jo Ki Hean Kim Seokchan Yoon Wonshik Choi |
| author_sort | Yongwoo Kwon |
| collection | DOAJ |
| description | The authors realize longitudinal deep-brain imaging through an intact mouse skull by constructing a high-speed reflection matrix microscope at 1.3 µm wavelength and developing a computational conjugate adaptive optics algorithm eliminating skull aberrations. |
| first_indexed | 2024-04-11T00:21:39Z |
| format | Article |
| id | doaj.art-379ba7ba16d845d9864032a255b064b7 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T00:21:39Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-379ba7ba16d845d9864032a255b064b72023-01-08T12:16:01ZengNature PortfolioNature Communications2041-17232023-01-011411910.1038/s41467-022-35738-9Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelinYongwoo Kwon0Jin Hee Hong1Sungsam Kang2Hojun Lee3Yonghyeon Jo4Ki Hean Kim5Seokchan Yoon6Wonshik Choi7Center for Molecular Spectroscopy and Dynamics, Institute for Basic ScienceCenter for Molecular Spectroscopy and Dynamics, Institute for Basic ScienceCenter for Molecular Spectroscopy and Dynamics, Institute for Basic ScienceCenter for Molecular Spectroscopy and Dynamics, Institute for Basic ScienceCenter for Molecular Spectroscopy and Dynamics, Institute for Basic ScienceDepartment of Mechanical Engineering, Pohang University of Science and TechnologyCenter for Molecular Spectroscopy and Dynamics, Institute for Basic ScienceCenter for Molecular Spectroscopy and Dynamics, Institute for Basic ScienceThe authors realize longitudinal deep-brain imaging through an intact mouse skull by constructing a high-speed reflection matrix microscope at 1.3 µm wavelength and developing a computational conjugate adaptive optics algorithm eliminating skull aberrations.https://doi.org/10.1038/s41467-022-35738-9 |
| spellingShingle | Yongwoo Kwon Jin Hee Hong Sungsam Kang Hojun Lee Yonghyeon Jo Ki Hean Kim Seokchan Yoon Wonshik Choi Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin Nature Communications |
| title | Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin |
| title_full | Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin |
| title_fullStr | Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin |
| title_full_unstemmed | Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin |
| title_short | Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin |
| title_sort | computational conjugate adaptive optics microscopy for longitudinal through skull imaging of cortical myelin |
| url | https://doi.org/10.1038/s41467-022-35738-9 |
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