Diabetic Ketoacidosis: Pattern of Precipitating Causes
Background: Diabetic ketoacidosis (DKA) is one of the most common acute complications of diabetes mellitus (DM). DKA is a recognised presenting feature of type 1 DM, but it commonly complicates previously diagnosed diabetic patients of all types, specially if they get infection or discontinue treatm...
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| Format: | Article |
| Language: | English |
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Enam Medical College, Dhaka
2014-05-01
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| Series: | Journal of Enam Medical College |
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| Online Access: | http://www.banglajol.info/index.php/JEMC/article/view/19676 |
| _version_ | 1811267489474019328 |
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| author | Ashraf Uddin Ahmed Muhammad Abdur Rahim Md Raziur Rahman Reshad Falah Nazim Khwaja Nazim Uddin |
| author_facet | Ashraf Uddin Ahmed Muhammad Abdur Rahim Md Raziur Rahman Reshad Falah Nazim Khwaja Nazim Uddin |
| author_sort | Ashraf Uddin Ahmed |
| collection | DOAJ |
| description | Background: Diabetic ketoacidosis (DKA) is one of the most common acute complications of diabetes mellitus (DM). DKA is a recognised presenting feature of type 1 DM, but it commonly complicates previously diagnosed diabetic patients of all types, specially if they get infection or discontinue treatment.
Objective: To describe the precipitating causes of DKA.
Materials and Methods: This cross-sectional study was done from September to November, 2010 in Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM). Diagnosed DKA cases were evaluated clinically and by laboratory investigations for identification of precipitating causes.
Results: Out of 50 patients, 28 were female. Mean age was 38.3 years. Forty patients (80%) were known diabetics and 10 (20%) were detected diabetic first time during this admission. Severe DKA cases were less common. Infection (20, 40%) was the commonest precipitating cause followed by noncompliance (14, 28%). In 7 (14%) cases no cause could be identified. Other less common causes included acute myocardial infarction, acute pancreatitis, stroke and surgery.
Conclusion: Infection and noncompliance were the major precipitants of DKA. So, it is assumed that many DKA cases might be prevented by proper counselling regarding adherence to medication and sick days’ management. |
| first_indexed | 2024-04-12T21:03:29Z |
| format | Article |
| id | doaj.art-379be9066f78478290b8c935be3a9dee |
| institution | Directory Open Access Journal |
| issn | 2227-6688 2304-9316 |
| language | English |
| last_indexed | 2024-04-12T21:03:29Z |
| publishDate | 2014-05-01 |
| publisher | Enam Medical College, Dhaka |
| record_format | Article |
| series | Journal of Enam Medical College |
| spelling | doaj.art-379be9066f78478290b8c935be3a9dee2022-12-22T03:16:47ZengEnam Medical College, DhakaJournal of Enam Medical College2227-66882304-93162014-05-0142949710.3329/jemc.v4i2.19676Diabetic Ketoacidosis: Pattern of Precipitating CausesAshraf Uddin Ahmed0Muhammad Abdur Rahim1Md Raziur Rahman2Reshad Falah Nazim3Khwaja Nazim Uddin4Medical Officer, Emergency Department, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, BangladeshRegistrar, Department of Medicine, Ibrahim Medical College and BIRDEM, Dhaka, BangladeshAssociate Professor, Department of Medicine, Ibrahim Medical College and BIRDEM, Dhaka, BangladeshLecturer, Department of Pathology, Ibrahim Medical College, Dhaka, BangladeshProfessor, Department of Medicine, Ibrahim Medical College and BIRDEM, Dhaka, BangladeshBackground: Diabetic ketoacidosis (DKA) is one of the most common acute complications of diabetes mellitus (DM). DKA is a recognised presenting feature of type 1 DM, but it commonly complicates previously diagnosed diabetic patients of all types, specially if they get infection or discontinue treatment. Objective: To describe the precipitating causes of DKA. Materials and Methods: This cross-sectional study was done from September to November, 2010 in Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM). Diagnosed DKA cases were evaluated clinically and by laboratory investigations for identification of precipitating causes. Results: Out of 50 patients, 28 were female. Mean age was 38.3 years. Forty patients (80%) were known diabetics and 10 (20%) were detected diabetic first time during this admission. Severe DKA cases were less common. Infection (20, 40%) was the commonest precipitating cause followed by noncompliance (14, 28%). In 7 (14%) cases no cause could be identified. Other less common causes included acute myocardial infarction, acute pancreatitis, stroke and surgery. Conclusion: Infection and noncompliance were the major precipitants of DKA. So, it is assumed that many DKA cases might be prevented by proper counselling regarding adherence to medication and sick days’ management.http://www.banglajol.info/index.php/JEMC/article/view/19676Diabetes mellitus; Diabetic ketoacidosis; Precipitating causes; Risk factors |
| spellingShingle | Ashraf Uddin Ahmed Muhammad Abdur Rahim Md Raziur Rahman Reshad Falah Nazim Khwaja Nazim Uddin Diabetic Ketoacidosis: Pattern of Precipitating Causes Journal of Enam Medical College Diabetes mellitus; Diabetic ketoacidosis; Precipitating causes; Risk factors |
| title | Diabetic Ketoacidosis: Pattern of Precipitating Causes |
| title_full | Diabetic Ketoacidosis: Pattern of Precipitating Causes |
| title_fullStr | Diabetic Ketoacidosis: Pattern of Precipitating Causes |
| title_full_unstemmed | Diabetic Ketoacidosis: Pattern of Precipitating Causes |
| title_short | Diabetic Ketoacidosis: Pattern of Precipitating Causes |
| title_sort | diabetic ketoacidosis pattern of precipitating causes |
| topic | Diabetes mellitus; Diabetic ketoacidosis; Precipitating causes; Risk factors |
| url | http://www.banglajol.info/index.php/JEMC/article/view/19676 |
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