Loss of cohesin regulator PDS5A reveals repressive role of Polycomb loops

Loss of cohesin regulator PDS5A reveals repressive role of Polycomb loops

Abstract Polycomb Repressive Complexes 1 and 2 (PRC1, PRC2) are conserved epigenetic regulators that promote transcriptional gene silencing. PRC1 and PRC2 converge on shared targets, catalyzing repressive histone modifications. Additionally, a subset of PRC1/PRC2 targets engage in long-range interac...

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Bibliographic Details
Main Authors:	Daniel Bsteh, Hagar F. Moussa, Georg Michlits, Ramesh Yelagandula, Jingkui Wang, Ulrich Elling, Oliver Bell
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-12-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-43869-w

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