Modulating Microglia/Macrophage Activation by CDNF Promotes Transplantation of Fetal Ventral Mesencephalic Graft Survival and Function in a Hemiparkinsonian Rat Model

Modulating Microglia/Macrophage Activation by CDNF Promotes Transplantation of Fetal Ventral Mesencephalic Graft Survival and Function in a Hemiparkinsonian Rat Model

Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons in substantia nigra pars compacta, which leads to the motor control deficits. Recently, cell transplantation is a cutting-edge technique for the therapy of PD. Nevertheless, one key bottleneck to realizing such potential i...

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Bibliographic Details
Main Authors:	Kuan-Yin Tseng, Jui-Sheng Wu, Yuan-Hao Chen, Mikko Airavaara, Cheng-Yi Cheng, Kuo-Hsing Ma
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Series:	Biomedicines
Subjects:	cerebral dopamine neurotrophic factor (CDNF) ventral mesencephalic tissue transplantation positron emission tomography Parkinson’s disease microglia activation
Online Access:	https://www.mdpi.com/2227-9059/10/6/1446

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