Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereus
The antibacterial activity and mechanism of rhamnolipids (RLs) against Bacillus cereus spores were analyzed from the aspects of appearance, morphology, and cell membrane state. The results showed that minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of RLs were 80....
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| Format: | Article |
| Language: | English |
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China Food Publishing Company
2024-03-01
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| Series: | Shipin Kexue |
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| Online Access: | https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-6-011.pdf |
| _version_ | 1827278923671535616 |
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| author | NIU Yongwu, QIAO Shan, SUN Yiming, WANG Yuchen, ZHAO Renyong, TIAN Shuangqi |
| author_facet | NIU Yongwu, QIAO Shan, SUN Yiming, WANG Yuchen, ZHAO Renyong, TIAN Shuangqi |
| author_sort | NIU Yongwu, QIAO Shan, SUN Yiming, WANG Yuchen, ZHAO Renyong, TIAN Shuangqi |
| collection | DOAJ |
| description | The antibacterial activity and mechanism of rhamnolipids (RLs) against Bacillus cereus spores were analyzed from the aspects of appearance, morphology, and cell membrane state. The results showed that minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of RLs were 80.0 and 160.0 mg/L, respectively. Both concentrations of RLs caused severe shrinkage and depression on the surface of spores, and disrupted the integrity and permeability of the spore cell membrane, leading to the leakage of intracellular electrolytes, DNA and proteins. In addition, RLs inhibited and inactivated B. cereus spores by various mechanisms such as decreasing heat resistance, generating oxidative stress, reducing surface adhesion, and binding to and interfering with DNA molecules. The results of this study will contribute to the development and application of RLs in the field of food safety. |
| first_indexed | 2024-04-24T08:09:09Z |
| format | Article |
| id | doaj.art-37a113e4ca5d4e20a6f605f5fa71cf87 |
| institution | Directory Open Access Journal |
| issn | 1002-6630 |
| language | English |
| last_indexed | 2024-04-24T08:09:09Z |
| publishDate | 2024-03-01 |
| publisher | China Food Publishing Company |
| record_format | Article |
| series | Shipin Kexue |
| spelling | doaj.art-37a113e4ca5d4e20a6f605f5fa71cf872024-04-17T07:13:34ZengChina Food Publishing CompanyShipin Kexue1002-66302024-03-01456808610.7506/spkx1002-6630-20230215-144Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereusNIU Yongwu, QIAO Shan, SUN Yiming, WANG Yuchen, ZHAO Renyong, TIAN Shuangqi0(1. College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, China; 2. National Engineering Research Center for Wheat & Corn Further Processing, Henan University of Technology, Zhengzhou 450001, China)The antibacterial activity and mechanism of rhamnolipids (RLs) against Bacillus cereus spores were analyzed from the aspects of appearance, morphology, and cell membrane state. The results showed that minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of RLs were 80.0 and 160.0 mg/L, respectively. Both concentrations of RLs caused severe shrinkage and depression on the surface of spores, and disrupted the integrity and permeability of the spore cell membrane, leading to the leakage of intracellular electrolytes, DNA and proteins. In addition, RLs inhibited and inactivated B. cereus spores by various mechanisms such as decreasing heat resistance, generating oxidative stress, reducing surface adhesion, and binding to and interfering with DNA molecules. The results of this study will contribute to the development and application of RLs in the field of food safety.https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-6-011.pdfrhamnolipids; bacillus cereus; spores; antibacterial mechanism |
| spellingShingle | NIU Yongwu, QIAO Shan, SUN Yiming, WANG Yuchen, ZHAO Renyong, TIAN Shuangqi Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereus Shipin Kexue rhamnolipids; bacillus cereus; spores; antibacterial mechanism |
| title | Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereus |
| title_full | Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereus |
| title_fullStr | Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereus |
| title_full_unstemmed | Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereus |
| title_short | Antibacterial Activity and Mechanism of Rhamnolipids against Bacillus cereus |
| title_sort | antibacterial activity and mechanism of rhamnolipids against bacillus cereus |
| topic | rhamnolipids; bacillus cereus; spores; antibacterial mechanism |
| url | https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-6-011.pdf |
| work_keys_str_mv | AT niuyongwuqiaoshansunyimingwangyuchenzhaorenyongtianshuangqi antibacterialactivityandmechanismofrhamnolipidsagainstbacilluscereus |