Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial
Objective: To examine the clinical effects of combining motor imagery-based neurofeedback training with bilateral repetitive transcranial magnetic stimulation for upper limb motor function in subacute and chronic stroke. Design: Clinical trial following an AB/BA crossover design with counterbalance...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Medical Journals Sweden
2024-03-01
|
| Series: | Journal of Rehabilitation Medicine |
| Subjects: | |
| Online Access: | https://medicaljournalssweden.se/jrm/article/view/18253 |
| _version_ | 1827324514487238656 |
|---|---|
| author | Francisco José Sánchez Cuesta Yeray González-Zamorano Marcos Moreno-Verdú Athanasios Vourvopoulos Ignacio J. Serrano Maria Dolores Del Castillo-Sobrino Patrícia Figueiredo Juan Pablo Romero |
| author_facet | Francisco José Sánchez Cuesta Yeray González-Zamorano Marcos Moreno-Verdú Athanasios Vourvopoulos Ignacio J. Serrano Maria Dolores Del Castillo-Sobrino Patrícia Figueiredo Juan Pablo Romero |
| author_sort | Francisco José Sánchez Cuesta |
| collection | DOAJ |
| description | Objective: To examine the clinical effects of combining motor imagery-based neurofeedback training with bilateral repetitive transcranial magnetic stimulation for upper limb motor function in subacute and chronic stroke.
Design: Clinical trial following an AB/BA crossover design with counterbalanced assignment.
Subjects: Twenty individuals with subacute (n = 4) or chronic stroke (n = 16).
Methods: Ten consecutive sessions of bilateral repetitive transcranial magnetic stimulation alone (therapy A) were compared vs a combination of10 consecutive sessions of bilateral repetitive transcranial magnetic stimulation with 12 non-consecutive sessions of motor imagery-based neurofeedback training (therapy B). Patients received both therapies (1-month washout period), in sequence AB or BA. Participants were assessed before and after each therapy and at 15-days follow-up, using the Fugl-Meyer Assessment-upper limb, hand-grip strength, and the Nottingham Sensory Assessment as primary outcome measures.
Results: Both therapies resulted in improved functionality and sensory function. Therapy B consistently exhibited superior effects compared with therapy A, according to Fugl-Meyer Assessment and tactile and kinaesthetic sensory function across multiple time-points, irrespective of treatment sequence. No statistically significant differences between therapies were found for hand-grip strength.
Conclusion: Following subacute and chronic stroke, integrating bilateral repetitive transcranial magnetic stimulation and motor imagery-based neurofeedback training has the potential to enhance functional performance compared with using bilateral repetitive transcranial magnetic stimulation alone in upper limb recovery.
|
| first_indexed | 2024-04-25T02:14:44Z |
| format | Article |
| id | doaj.art-37a2c6ade71f4d04b52da259b89b66bd |
| institution | Directory Open Access Journal |
| issn | 1651-2081 |
| language | English |
| last_indexed | 2024-04-25T02:14:44Z |
| publishDate | 2024-03-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Journal of Rehabilitation Medicine |
| spelling | doaj.art-37a2c6ade71f4d04b52da259b89b66bd2024-03-07T09:11:13ZengMedical Journals SwedenJournal of Rehabilitation Medicine1651-20812024-03-015610.2340/jrm.v56.18253Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trialFrancisco José Sánchez Cuesta0Yeray González-Zamorano1Marcos Moreno-Verdú2Athanasios Vourvopoulos3Ignacio J. Serrano4Maria Dolores Del Castillo-Sobrino5Patrícia Figueiredo6Juan Pablo Romero7Faculty of Experimental Sciences, Francisco de Vitoria University, Pozuelo de Alarcón, Spain; Brain Injury and Movement Disorders Neurorehabilitation Group (GINDAT), Institute of Life Sciences, Francisco de Vitoria University, Pozuelo de Alarcón, SpainBrain Injury and Movement Disorders Neurorehabilitation Group (GINDAT), Institute of Life Sciences, Francisco de Vitoria University, Pozuelo de Alarcón, Spain; Department of Physiotherapy, Occupational Therapy, Rehabilitation and Physical Medicine, King Juan Carlos University, Alcorcón, Spain; Cognitive Neuroscience, Pain, and Rehabilitation Research Group (NECODOR), Faculty of Health Sciences, Rey Juan Carlos University, Madrid, SpainFaculty of Experimental Sciences, Francisco de Vitoria University, Pozuelo de Alarcón, Spain; Brain Injury and Movement Disorders Neurorehabilitation Group (GINDAT), Institute of Life Sciences, Francisco de Vitoria University, Pozuelo de Alarcón, SpainInstitute for Systems and Robotics-Lisboa, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, PortugalNeural and Cognitive Engineering group, Centre for Automation and Robotics (CAR) CSIC-UPM, Arganda del Rey, Madrid, SpainNeural and Cognitive Engineering group, Centre for Automation and Robotics (CAR) CSIC-UPM, Arganda del Rey, Madrid, SpainInstitute for Systems and Robotics-Lisboa, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, PortugalFaculty of Experimental Sciences, Francisco de Vitoria University, Pozuelo de Alarcón, Spain; Brain Injury and Movement Disorders Neurorehabilitation Group (GINDAT), Institute of Life Sciences, Francisco de Vitoria University, Pozuelo de Alarcón, Spain; Brain Damage Unit, Beata María Ana Hospital, Madrid, SpainObjective: To examine the clinical effects of combining motor imagery-based neurofeedback training with bilateral repetitive transcranial magnetic stimulation for upper limb motor function in subacute and chronic stroke. Design: Clinical trial following an AB/BA crossover design with counterbalanced assignment. Subjects: Twenty individuals with subacute (n = 4) or chronic stroke (n = 16). Methods: Ten consecutive sessions of bilateral repetitive transcranial magnetic stimulation alone (therapy A) were compared vs a combination of10 consecutive sessions of bilateral repetitive transcranial magnetic stimulation with 12 non-consecutive sessions of motor imagery-based neurofeedback training (therapy B). Patients received both therapies (1-month washout period), in sequence AB or BA. Participants were assessed before and after each therapy and at 15-days follow-up, using the Fugl-Meyer Assessment-upper limb, hand-grip strength, and the Nottingham Sensory Assessment as primary outcome measures. Results: Both therapies resulted in improved functionality and sensory function. Therapy B consistently exhibited superior effects compared with therapy A, according to Fugl-Meyer Assessment and tactile and kinaesthetic sensory function across multiple time-points, irrespective of treatment sequence. No statistically significant differences between therapies were found for hand-grip strength. Conclusion: Following subacute and chronic stroke, integrating bilateral repetitive transcranial magnetic stimulation and motor imagery-based neurofeedback training has the potential to enhance functional performance compared with using bilateral repetitive transcranial magnetic stimulation alone in upper limb recovery. https://medicaljournalssweden.se/jrm/article/view/18253repetitive transcranial magnetic stimulationrTMSmotor imageryneurofeedbackstrokemotor cortex |
| spellingShingle | Francisco José Sánchez Cuesta Yeray González-Zamorano Marcos Moreno-Verdú Athanasios Vourvopoulos Ignacio J. Serrano Maria Dolores Del Castillo-Sobrino Patrícia Figueiredo Juan Pablo Romero Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial Journal of Rehabilitation Medicine repetitive transcranial magnetic stimulation rTMS motor imagery neurofeedback stroke motor cortex |
| title | Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial |
| title_full | Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial |
| title_fullStr | Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial |
| title_full_unstemmed | Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial |
| title_short | Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial |
| title_sort | effects of motor imagery based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post stroke upper limb motor function an exploratory crossover clinical trial |
| topic | repetitive transcranial magnetic stimulation rTMS motor imagery neurofeedback stroke motor cortex |
| url | https://medicaljournalssweden.se/jrm/article/view/18253 |
| work_keys_str_mv | AT franciscojosesanchezcuesta effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial AT yeraygonzalezzamorano effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial AT marcosmorenoverdu effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial AT athanasiosvourvopoulos effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial AT ignaciojserrano effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial AT mariadoloresdelcastillosobrino effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial AT patriciafigueiredo effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial AT juanpabloromero effectsofmotorimagerybasedneurofeedbacktrainingafterbilateralrepetitivetranscranialmagneticstimulationonpoststrokeupperlimbmotorfunctionanexploratorycrossoverclinicaltrial |