Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages

The data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS–TOF/TOF. All newborns were separated into three gestational age groups, &qu...

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Main Authors: M.D. Ruiz-González, M.D. Cañete, J.L. Gómez-Chaparro, A. Rodríguez-Torronteras, N. Abril, R. Cañete, J.L. López-Barea
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Data in Brief
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340916305960
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author M.D. Ruiz-González
M.D. Cañete
J.L. Gómez-Chaparro
A. Rodríguez-Torronteras
N. Abril
R. Cañete
J.L. López-Barea
author_facet M.D. Ruiz-González
M.D. Cañete
J.L. Gómez-Chaparro
A. Rodríguez-Torronteras
N. Abril
R. Cañete
J.L. López-Barea
author_sort M.D. Ruiz-González
collection DOAJ
description The data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS–TOF/TOF. All newborns were separated into three gestational age groups, "Very Preterm" 29–32 weeks, "Moderate Preterm" 33–36 weeks, and, "Term" ≥37weeks. From each newborn, blood was drawn three times from birth to 1 month life. High-abundant serum proteins were depleted, and the minority ones were separated by 2DE and analyzed for significant expression differences. The data reflect analytic and clinic variables analyzed globally and categorized by gestational age in relation to IUGR and the optimization of conditions for 2-DE separation. The data from this study are related to the research article entitled "Alterations of Protein Expression in Serum of Infants with Intrauterine Growth Restriction and Different Gestational Ages" (M.D. Ruis-González, M.D. Cañete, J.L. Gómez-Chaparro, N. Abril, R. Cañete, J. López-Barea, 2015) [1]. The present dataset of serum IUGR newborn proteome can be used as a reference for any study involving intrauterine growth restriction during the first month of life.
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spelling doaj.art-37a661c1bdc74b3eaf44875ba51ee6302022-12-22T00:12:10ZengElsevierData in Brief2352-34092016-12-019C43844710.1016/j.dib.2016.09.024Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational agesM.D. Ruiz-González0M.D. Cañete1J.L. Gómez-Chaparro2A. Rodríguez-Torronteras3N. Abril4R. Cañete5J.L. López-Barea6Neonatology Unit, Pediatrics Service, Reina Sofía University Hospital, Andalusian Health Service, Menéndez Pidal Avenue, 14004 Córdoba, SpainMaimonides Institute of Biomedical Research of Córdoba (IMIBIC), Menendez Pidal Avenue, 14004 Córdoba, SpainExperimental Unit Córdoba District, Andalusian Health Service, Isla Lanzarote s/n, 14011 Córdoba, SpainEpidemiology Unit Córdoba District, Andalusian Health Service, Isla Lanzarote s/n, 14011 Córdoba, SpainDepartment of Biochemistry and Molecular Biology, Severo Ochoa Building, Rabanales Campus, University of Córdoba, A4 highway, Km 396a, 14071 Córdoba, SpainPediatric Endocrinology Section, Pediatrics Service, Reina Sofía University Hospital, Andalusian Health Service, Menéndez Pidal Avenue, 14004 Córdoba, SpainDepartment of Biochemistry and Molecular Biology, Severo Ochoa Building, Rabanales Campus, University of Córdoba, A4 highway, Km 396a, 14071 Córdoba, SpainThe data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS–TOF/TOF. All newborns were separated into three gestational age groups, "Very Preterm" 29–32 weeks, "Moderate Preterm" 33–36 weeks, and, "Term" ≥37weeks. From each newborn, blood was drawn three times from birth to 1 month life. High-abundant serum proteins were depleted, and the minority ones were separated by 2DE and analyzed for significant expression differences. The data reflect analytic and clinic variables analyzed globally and categorized by gestational age in relation to IUGR and the optimization of conditions for 2-DE separation. The data from this study are related to the research article entitled "Alterations of Protein Expression in Serum of Infants with Intrauterine Growth Restriction and Different Gestational Ages" (M.D. Ruis-González, M.D. Cañete, J.L. Gómez-Chaparro, N. Abril, R. Cañete, J. López-Barea, 2015) [1]. The present dataset of serum IUGR newborn proteome can be used as a reference for any study involving intrauterine growth restriction during the first month of life.http://www.sciencedirect.com/science/article/pii/S2352340916305960Human newbornIntrauterine growth restrictionVenous bloodSerum proteinsProteomics
spellingShingle M.D. Ruiz-González
M.D. Cañete
J.L. Gómez-Chaparro
A. Rodríguez-Torronteras
N. Abril
R. Cañete
J.L. López-Barea
Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
Data in Brief
Human newborn
Intrauterine growth restriction
Venous blood
Serum proteins
Proteomics
title Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_full Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_fullStr Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_full_unstemmed Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_short Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages
title_sort morbility clinical data and proteomic analysis of iugr and aga newborns at different gestational ages
topic Human newborn
Intrauterine growth restriction
Venous blood
Serum proteins
Proteomics
url http://www.sciencedirect.com/science/article/pii/S2352340916305960
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