Cell technologies as a platform for personalized therapy: global challenges in oncology

The incidence of various types of cancer is steadily increasing. It is necessary to correctly analyze and interpret statistical data, given that the quality of medical care at all its stages is characterized not by the level of morbidity, but by the mortality rate. The leading centers of the Russian...

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Main Authors: M. Yu. Rykov, G. L. Mentkevich, I. S. Dolgopolov
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2022-08-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/1645
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author M. Yu. Rykov
G. L. Mentkevich
I. S. Dolgopolov
author_facet M. Yu. Rykov
G. L. Mentkevich
I. S. Dolgopolov
author_sort M. Yu. Rykov
collection DOAJ
description The incidence of various types of cancer is steadily increasing. It is necessary to correctly analyze and interpret statistical data, given that the quality of medical care at all its stages is characterized not by the level of morbidity, but by the mortality rate. The leading centers of the Russian Federation can apply almost all the therapy methods to treat patients. At the same time, one of the limiting factors for increasing the survival rate is the detection of diseases mainly at the late stages, which dictates the need to increase oncological alertness and the widespread introduction of early screening diagnostics into healthcare practice. The development of many new targeted drugs has led to the fact that only a few have been shown to be effective in the treatment of only certain types of tumors. The development of bone marrow transplantation contributed to the development of other directions in medicine, which proved that the hematopoietic stem cell is a platform for personalized therapy for many diseases. The article describes the problems of cell therapy implementation in the treatment of cancer patients.
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spelling doaj.art-37a90092cb084081be380832cf4202342023-03-13T09:12:52ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282022-08-0167351010.21508/1027-4065-2022-67-3-5-101193Cell technologies as a platform for personalized therapy: global challenges in oncologyM. Yu. Rykov0G. L. Mentkevich1I. S. Dolgopolov2ФГБОУ ВО «Тверской государственный медицинский университет» Минздрава России; ФГБНУ ВО «Национальный научно-исследовательский институт общественного здоровья имени Н.А. Семашко»ФГБОУ ВО «Тверской государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Тверской государственный медицинский университет» Минздрава РоссииThe incidence of various types of cancer is steadily increasing. It is necessary to correctly analyze and interpret statistical data, given that the quality of medical care at all its stages is characterized not by the level of morbidity, but by the mortality rate. The leading centers of the Russian Federation can apply almost all the therapy methods to treat patients. At the same time, one of the limiting factors for increasing the survival rate is the detection of diseases mainly at the late stages, which dictates the need to increase oncological alertness and the widespread introduction of early screening diagnostics into healthcare practice. The development of many new targeted drugs has led to the fact that only a few have been shown to be effective in the treatment of only certain types of tumors. The development of bone marrow transplantation contributed to the development of other directions in medicine, which proved that the hematopoietic stem cell is a platform for personalized therapy for many diseases. The article describes the problems of cell therapy implementation in the treatment of cancer patients.https://www.ped-perinatology.ru/jour/article/view/1645детионкологиядетская онкологияклеточные технологиитрансплантация костного мозгагемопоэтическая стволовая клеткадендритные вакцины
spellingShingle M. Yu. Rykov
G. L. Mentkevich
I. S. Dolgopolov
Cell technologies as a platform for personalized therapy: global challenges in oncology
Rossijskij Vestnik Perinatologii i Pediatrii
дети
онкология
детская онкология
клеточные технологии
трансплантация костного мозга
гемопоэтическая стволовая клетка
дендритные вакцины
title Cell technologies as a platform for personalized therapy: global challenges in oncology
title_full Cell technologies as a platform for personalized therapy: global challenges in oncology
title_fullStr Cell technologies as a platform for personalized therapy: global challenges in oncology
title_full_unstemmed Cell technologies as a platform for personalized therapy: global challenges in oncology
title_short Cell technologies as a platform for personalized therapy: global challenges in oncology
title_sort cell technologies as a platform for personalized therapy global challenges in oncology
topic дети
онкология
детская онкология
клеточные технологии
трансплантация костного мозга
гемопоэтическая стволовая клетка
дендритные вакцины
url https://www.ped-perinatology.ru/jour/article/view/1645
work_keys_str_mv AT myurykov celltechnologiesasaplatformforpersonalizedtherapyglobalchallengesinoncology
AT glmentkevich celltechnologiesasaplatformforpersonalizedtherapyglobalchallengesinoncology
AT isdolgopolov celltechnologiesasaplatformforpersonalizedtherapyglobalchallengesinoncology