The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report
Background: Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Exercise training exerts beneficial effects on adipose tissue. However, less is known regarding visfatin’s, IL-6 & TNF-α response to an interval acute training. Therefore, we investigated the...
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Tehran University of Medical Sciences
2013-12-01
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| Series: | Tehran University Medical Journal |
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| Online Access: | http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5150&slc_lang=en&sid=1 |
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| author | Farhad Daryanoosh Hossein Jafari Eskandar Rahimi Davood Mehrbani Firouz Soltani |
| author_facet | Farhad Daryanoosh Hossein Jafari Eskandar Rahimi Davood Mehrbani Firouz Soltani |
| author_sort | Farhad Daryanoosh |
| collection | DOAJ |
| description | Background: Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Exercise training exerts beneficial effects on adipose tissue. However, less is known regarding visfatin’s, IL-6 & TNF-α response to an interval acute training. Therefore, we investigated the effects of acute interval exercise on plasma visfatin, TNF-α and IL-6 levels, in healthy female rats. Furthermore, correlate between changes probably these factors were also assessed.Methods: This study was conducted experimentally. Forty five female sprague dawley rat were randomly divided into three groups: pre test (n= 15), treadmill exercise (n= 15) and sedentary controls (n= 15). The acute alternative exercise consisted of treadmill running: 3 session/ week for 8 week. The changes of plasma IL-6, TNF-α and Visfatin levels were measured by ELISA analysis. Data were analyzed using analysis of variance with measures (ANOVA) and post hoc Tukey test.Results: Acute interval treadmill exercise led to significant decreases in visfatin (P= 0/036), IL-6 (P= 0/009) and TNF-α (P= 0/022) plasma levels between the groups. Also, this study no significant correlations between the changes in adipokines were observed.Conclusion: Decreased levels of TNF-α and IL-6 correlated with intensity and duration exercise. Furthermore, probably there were some factors except weight decreasing that affects on visfatin decrease. Therefore, the reduction of this factor may cause in preventing metabolic disease. |
| first_indexed | 2024-12-11T22:52:29Z |
| format | Article |
| id | doaj.art-37ac294e6bc340f19c037db08450071a |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-12-11T22:52:29Z |
| publishDate | 2013-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-37ac294e6bc340f19c037db08450071a2022-12-22T00:47:24ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222013-12-01719603608The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief reportFarhad Daryanoosh 0Hossein Jafari 1Eskandar Rahimi 2Davood Mehrbani 3Firouz Soltani 4 Department of Physical Education, Faculty of Education and Psychology, Shiraz University, Shiraz, Iran. Department of Exercise Physiology, Shiraz University, Shiraz, Iran. Department of Physical Education, Islamic Azad University of Shiraz, Shiraz, Iran. Shiraz University of Medical Science, Shiraz, Iran. Department of Exercise Physiology, Shiraz University, Shiraz, Iran. Background: Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Exercise training exerts beneficial effects on adipose tissue. However, less is known regarding visfatin’s, IL-6 & TNF-α response to an interval acute training. Therefore, we investigated the effects of acute interval exercise on plasma visfatin, TNF-α and IL-6 levels, in healthy female rats. Furthermore, correlate between changes probably these factors were also assessed.Methods: This study was conducted experimentally. Forty five female sprague dawley rat were randomly divided into three groups: pre test (n= 15), treadmill exercise (n= 15) and sedentary controls (n= 15). The acute alternative exercise consisted of treadmill running: 3 session/ week for 8 week. The changes of plasma IL-6, TNF-α and Visfatin levels were measured by ELISA analysis. Data were analyzed using analysis of variance with measures (ANOVA) and post hoc Tukey test.Results: Acute interval treadmill exercise led to significant decreases in visfatin (P= 0/036), IL-6 (P= 0/009) and TNF-α (P= 0/022) plasma levels between the groups. Also, this study no significant correlations between the changes in adipokines were observed.Conclusion: Decreased levels of TNF-α and IL-6 correlated with intensity and duration exercise. Furthermore, probably there were some factors except weight decreasing that affects on visfatin decrease. Therefore, the reduction of this factor may cause in preventing metabolic disease.http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5150&slc_lang=en&sid=1adipokines exercise interleukin-6 metabolic disease tumor necrosis factor-alpha |
| spellingShingle | Farhad Daryanoosh Hossein Jafari Eskandar Rahimi Davood Mehrbani Firouz Soltani The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report Tehran University Medical Journal adipokines exercise interleukin-6 metabolic disease tumor necrosis factor-alpha |
| title | The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report |
| title_full | The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report |
| title_fullStr | The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report |
| title_full_unstemmed | The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report |
| title_short | The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report |
| title_sort | effect of eight week interval acute training on plasma visfatin tnf α and il 6 in rats a brief report |
| topic | adipokines exercise interleukin-6 metabolic disease tumor necrosis factor-alpha |
| url | http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5150&slc_lang=en&sid=1 |
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