Mucoadhesive cellulose Nanocrystal-chitosan nanocomposite for the delivery of hydrophobic compounds

Mucoadhesive cellulose Nanocrystal-chitosan nanocomposite for the delivery of hydrophobic compounds

Cellulose nanocrystals (CNC) have received much attention as a drug delivery vehicle, but their hydrophilic nature hinders hydrophobic drug loading. Ionotropic gelation using CNC and chitosan (CS) can enhance the loading/encapsulation capacity of hydrophobic compounds, improve colloidal stability, a...

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Bibliographic Details
Main Authors: Dae Sung Kim, Fatemah Haji, Joseph Jun, Jiyoo Baek, Lian Han, Peter Wu, Brian Dixon, Kam C. Tam
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:JCIS Open
Subjects:
Mucoadhesive drug delivery
Cellulose nanocrystals
Chitosan
Hydrophobic drug encapsulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666934X23000193

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