Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies
Multiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experienced a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. Recent advancements in stem cell therapies may serve as potential treatments for neurolog...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2013-01-01
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| Series: | International Journal of Hematology-Oncology and Stem Cell Research |
| Subjects: | |
| Online Access: | http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/357/452 |
| _version_ | 1797710219783962624 |
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| author | Abdolreza Ardeshirylajimi Majid Farshdousti Hagh Najmaldin Saki Esmaeil Mortaz Masoud Soleimani Fakher Rahim |
| author_facet | Abdolreza Ardeshirylajimi Majid Farshdousti Hagh Najmaldin Saki Esmaeil Mortaz Masoud Soleimani Fakher Rahim |
| author_sort | Abdolreza Ardeshirylajimi |
| collection | DOAJ |
| description | Multiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experienced a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. Recent advancements in stem cell therapies may serve as potential treatments for neurological disorders. There are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS. |
| first_indexed | 2024-03-12T06:49:01Z |
| format | Article |
| id | doaj.art-37bff6e1edd54c47b97984055c988305 |
| institution | Directory Open Access Journal |
| issn | 2008-3009 2008-2207 |
| language | English |
| last_indexed | 2024-03-12T06:49:01Z |
| publishDate | 2013-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | International Journal of Hematology-Oncology and Stem Cell Research |
| spelling | doaj.art-37bff6e1edd54c47b97984055c9883052023-09-03T00:25:07ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-30092008-22072013-01-01711330Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 StudiesAbdolreza ArdeshirylajimiMajid Farshdousti HaghNajmaldin SakiEsmaeil MortazMasoud SoleimaniFakher RahimMultiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experienced a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. Recent advancements in stem cell therapies may serve as potential treatments for neurological disorders. There are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS.http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/357/452Multiple SclerosisStem Cells TherapyHuman Embryonic Stem CellsHematopoietic Stem CellsMesenchymal Stem CellsNeural Stem Cells |
| spellingShingle | Abdolreza Ardeshirylajimi Majid Farshdousti Hagh Najmaldin Saki Esmaeil Mortaz Masoud Soleimani Fakher Rahim Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies International Journal of Hematology-Oncology and Stem Cell Research Multiple Sclerosis Stem Cells Therapy Human Embryonic Stem Cells Hematopoietic Stem Cells Mesenchymal Stem Cells Neural Stem Cells |
| title | Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies |
| title_full | Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies |
| title_fullStr | Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies |
| title_full_unstemmed | Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies |
| title_short | Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies |
| title_sort | feasibility of cell therapy in multiple sclerosis a systematic review of 83 studies |
| topic | Multiple Sclerosis Stem Cells Therapy Human Embryonic Stem Cells Hematopoietic Stem Cells Mesenchymal Stem Cells Neural Stem Cells |
| url | http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/357/452 |
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