Differential Regulation of Human Treg and Th17 Cells by Fatty Acid Synthesis and Glycolysis
In this study we examined the metabolic requirements of human T helper cells and the effect of manipulating metabolic pathways in Th17 and Treg cells. The Th17:Treg cell axis is dysregulated in a number of autoimmune or inflammatory diseases and therefore it is of key importance to identify novel st...
Main Authors: | Deborah Cluxton, Andreea Petrasca, Barry Moran, Jean M. Fletcher |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-02-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.00115/full |
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