Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in Tunisia
This research aimed to study the chemical composition of <i>Aloysia</i> <i>citrodora</i> methanolic extract and its biological activities as an antioxidant, and its antibacterial, antifungal and anti-inflammatory activities based on four bioclimatic collection stages. The con...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/10/12/2912 |
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| author | Sonia Tammar Nidhal Salem Wissem Aidi Wannes Hajer Limam Soumaya Bourgou Nedia Fares Sarra Dakhlaoui Majdi Hammami Saber Khammassi Giovanni Del Re Kamel Hessini Kamel Msaada |
| author_facet | Sonia Tammar Nidhal Salem Wissem Aidi Wannes Hajer Limam Soumaya Bourgou Nedia Fares Sarra Dakhlaoui Majdi Hammami Saber Khammassi Giovanni Del Re Kamel Hessini Kamel Msaada |
| author_sort | Sonia Tammar |
| collection | DOAJ |
| description | This research aimed to study the chemical composition of <i>Aloysia</i> <i>citrodora</i> methanolic extract and its biological activities as an antioxidant, and its antibacterial, antifungal and anti-inflammatory activities based on four bioclimatic collection stages. The contents of total phenols, total flavonoids and total tannins were determined. Nine phenolic compounds were identified by LC-DAD–ESI-MS/MS. The major compound was acteoside, a phenylpropanoid which represented about 80% of the methanolic fraction in the various regions. The antioxidant activities of different locations were measured by different analytical assays, such as DPPH, ABTS and iron reducing power. The results showed that phenolic compounds and antioxidant activities varied with climatic and environmental factors. Moreover, there was a significant dependency between regions and biological activities. The use of a principal component analysis showed that there was a close relationship among phenylpropanoids, phenolic compounds and the studied biological activities. |
| first_indexed | 2024-03-10T04:08:59Z |
| format | Article |
| id | doaj.art-37c1b676196c43cc92f9e4dc5f709771 |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T04:08:59Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-37c1b676196c43cc92f9e4dc5f7097712023-11-23T08:16:09ZengMDPI AGFoods2304-81582021-11-011012291210.3390/foods10122912Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in TunisiaSonia Tammar0Nidhal Salem1Wissem Aidi Wannes2Hajer Limam3Soumaya Bourgou4Nedia Fares5Sarra Dakhlaoui6Majdi Hammami7Saber Khammassi8Giovanni Del Re9Kamel Hessini10Kamel Msaada11Laboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaLaboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaDipartimento di Ingegneria Industriale e dell’ Informazione e di Economia, Università dell’Aquila, Piazzale Ernesto Pontieri, Monteluco di Roio, 67100 L’Aquila, ItalyDepartment of Biology, College of Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi ArabiaLaboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopol, BP. 901, Hammam-Lif 2050, TunisiaThis research aimed to study the chemical composition of <i>Aloysia</i> <i>citrodora</i> methanolic extract and its biological activities as an antioxidant, and its antibacterial, antifungal and anti-inflammatory activities based on four bioclimatic collection stages. The contents of total phenols, total flavonoids and total tannins were determined. Nine phenolic compounds were identified by LC-DAD–ESI-MS/MS. The major compound was acteoside, a phenylpropanoid which represented about 80% of the methanolic fraction in the various regions. The antioxidant activities of different locations were measured by different analytical assays, such as DPPH, ABTS and iron reducing power. The results showed that phenolic compounds and antioxidant activities varied with climatic and environmental factors. Moreover, there was a significant dependency between regions and biological activities. The use of a principal component analysis showed that there was a close relationship among phenylpropanoids, phenolic compounds and the studied biological activities.https://www.mdpi.com/2304-8158/10/12/2912<i>Aloysia</i> <i>citrodora</i>phenolic compoundsantioxidant activityantibacterial activityantifungal activityanti-inflammatory activity |
| spellingShingle | Sonia Tammar Nidhal Salem Wissem Aidi Wannes Hajer Limam Soumaya Bourgou Nedia Fares Sarra Dakhlaoui Majdi Hammami Saber Khammassi Giovanni Del Re Kamel Hessini Kamel Msaada Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in Tunisia Foods <i>Aloysia</i> <i>citrodora</i> phenolic compounds antioxidant activity antibacterial activity antifungal activity anti-inflammatory activity |
| title | Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in Tunisia |
| title_full | Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in Tunisia |
| title_fullStr | Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in Tunisia |
| title_full_unstemmed | Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in Tunisia |
| title_short | Chemometric Profiling and Bioactivity of Verbena (<i>Aloysia</i> <i>citrodora</i>) Methanolic Extract from Four Localities in Tunisia |
| title_sort | chemometric profiling and bioactivity of verbena i aloysia i i citrodora i methanolic extract from four localities in tunisia |
| topic | <i>Aloysia</i> <i>citrodora</i> phenolic compounds antioxidant activity antibacterial activity antifungal activity anti-inflammatory activity |
| url | https://www.mdpi.com/2304-8158/10/12/2912 |
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