Ssl2/TFIIH function in transcription start site scanning by RNA polymerase II in Saccharomyces cerevisiae

Ssl2/TFIIH function in transcription start site scanning by RNA polymerase II in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, RNA polymerase II (Pol II) selects transcription start sites (TSSs) by a unidirectional scanning process. During scanning, a preinitiation complex (PIC) assembled at an upstream core promoter initiates at select positions within a window ~40–120 bp downstream. Several li...

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Bibliographic Details
Main Authors: Tingting Zhao, Irina O Vvedenskaya, William KM Lai, Shrabani Basu, B Franklin Pugh, Bryce E Nickels, Craig D Kaplan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-10-01
Series:eLife
Subjects:
transcription initiation
RNA polymerase II
yeast
general transcription factors
transcription start site
Online Access:https://elifesciences.org/articles/71013

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