The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective Study
<i>Background and Objectives</i>: The risk of bleeding after endoscopic procedures in patients with liver cirrhosis remains unclear because of secondary blood coagulation disorders. In this study, we used various indices to evaluate the risk of bleeding in patients with cirrhosis. <i&...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/1/170 |
| _version_ | 1797438854667436032 |
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| author | Su Bee Park Jung Won Jeon Hyun Phil Shin |
| author_facet | Su Bee Park Jung Won Jeon Hyun Phil Shin |
| author_sort | Su Bee Park |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: The risk of bleeding after endoscopic procedures in patients with liver cirrhosis remains unclear because of secondary blood coagulation disorders. In this study, we used various indices to evaluate the risk of bleeding in patients with cirrhosis. <i>Materials and Methods</i>: Patients with liver cirrhosis aged ≥18 years who underwent endoscopic interventions at Kyung Hee University Hospital at Gangdong between February 2007 and September 2021 were included. Clinical information, including demographic data, laboratory results, the presence of cirrhosis complications, and the degree of fibrosis, was checked and evaluated based on medical records. <i>Results</i>: A total of 101 patients with cirrhosis were analyzed. A total of 16 of the 101 patients (15.8%) experienced bleeding after the endoscopic procedure. One patient (0.99%) presented with spurting, while the others presented with mild oozing. All patients underwent hemostatic procedures using hemoclips. The presence of a varix significantly increased post-endoscopic bleeding (<i>p</i> = 0.03). Patients with FIB > 3.25 showed a statistically significant bleeding tendency (<i>p</i> = 0.00). <i>Conclusions</i>: There was no significant difference in bleeding risk according to the platelet count, prothrombin time, Child–Pugh score, and model for end-stage liver disease (MELD). Considering the degree of liver fibrosis and the invasiveness of the planned procedure, most endoscopic procedures can be performed safely but should be further evaluated in a cohort with a larger sample size. |
| first_indexed | 2024-03-09T11:44:19Z |
| format | Article |
| id | doaj.art-37c405d1b3f846219756758df33f7b8f |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T11:44:19Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-37c405d1b3f846219756758df33f7b8f2023-11-30T23:25:25ZengMDPI AGMedicina1010-660X1648-91442023-01-0159117010.3390/medicina59010170The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective StudySu Bee Park0Jung Won Jeon1Hyun Phil Shin2Division of Gastroenterology, Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, Kyung Hee University College of Medicine, Seoul 05278, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, Kyung Hee University College of Medicine, Seoul 05278, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, Kyung Hee University College of Medicine, Seoul 05278, Republic of Korea<i>Background and Objectives</i>: The risk of bleeding after endoscopic procedures in patients with liver cirrhosis remains unclear because of secondary blood coagulation disorders. In this study, we used various indices to evaluate the risk of bleeding in patients with cirrhosis. <i>Materials and Methods</i>: Patients with liver cirrhosis aged ≥18 years who underwent endoscopic interventions at Kyung Hee University Hospital at Gangdong between February 2007 and September 2021 were included. Clinical information, including demographic data, laboratory results, the presence of cirrhosis complications, and the degree of fibrosis, was checked and evaluated based on medical records. <i>Results</i>: A total of 101 patients with cirrhosis were analyzed. A total of 16 of the 101 patients (15.8%) experienced bleeding after the endoscopic procedure. One patient (0.99%) presented with spurting, while the others presented with mild oozing. All patients underwent hemostatic procedures using hemoclips. The presence of a varix significantly increased post-endoscopic bleeding (<i>p</i> = 0.03). Patients with FIB > 3.25 showed a statistically significant bleeding tendency (<i>p</i> = 0.00). <i>Conclusions</i>: There was no significant difference in bleeding risk according to the platelet count, prothrombin time, Child–Pugh score, and model for end-stage liver disease (MELD). Considering the degree of liver fibrosis and the invasiveness of the planned procedure, most endoscopic procedures can be performed safely but should be further evaluated in a cohort with a larger sample size.https://www.mdpi.com/1648-9144/59/1/170liver cirrhosisendoscopic procedurebleedingfibrosis |
| spellingShingle | Su Bee Park Jung Won Jeon Hyun Phil Shin The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective Study Medicina liver cirrhosis endoscopic procedure bleeding fibrosis |
| title | The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective Study |
| title_full | The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective Study |
| title_fullStr | The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective Study |
| title_full_unstemmed | The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective Study |
| title_short | The Risk of Endoscopy-Related Bleeding in Patients with Liver Cirrhosis: A Retrospective Study |
| title_sort | risk of endoscopy related bleeding in patients with liver cirrhosis a retrospective study |
| topic | liver cirrhosis endoscopic procedure bleeding fibrosis |
| url | https://www.mdpi.com/1648-9144/59/1/170 |
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