Amoxicillin and Clarithromycin Mucoadhesive Delivery System for <i>Helicobacter pylori</i> Infection in a Mouse Model: Characterization, Pharmacokinetics, and Efficacy

Amoxicillin and Clarithromycin Mucoadhesive Delivery System for <i>Helicobacter pylori</i> Infection in a Mouse Model: Characterization, Pharmacokinetics, and Efficacy

<i>Helicobacter pylori</i> is the main pathogen responsible for gastric ulcers and a predisposing factor of stomach cancer. Although current treatment is usually successful, it requires high doses and frequent administration. An innovative mucoadhesive system (Mucolast<sup>®</su...

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Bibliographic Details
Main Authors: Isabel Villegas, María Ángeles Rosillo, Catalina Alarcón-de-la-Lastra, Victoria Vázquez-Román, Maria Llorente, Susana Sánchez, Ana Gloria Gil, Pilar Alcalde, Esther González, Elisabet Rosell, Carles Nieto, Francisco Fernandez-Campos
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
<i>Helicobacter pylori</i>
mucoadhesive
clarithromycin
amoxicillin
mice
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/13/2/153

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