Gardnerella vaginalis alters cervicovaginal epithelial cell function through microbe-specific immune responses

Gardnerella vaginalis alters cervicovaginal epithelial cell function through microbe-specific immune responses

Abstract Background The cervicovaginal (CV) microbiome is highly associated with vaginal health and disease in both pregnant and nonpregnant individuals. An overabundance of Gardnerella vaginalis (G. vaginalis) in the CV space is commonly associated with adverse reproductive outcomes including bacte...

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Bibliographic Details
Main Authors: Lauren Anton, Briana Ferguson, Elliot S. Friedman, Kristin D. Gerson, Amy G. Brown, Michal A. Elovitz
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Microbiome
Subjects:
Cervix
Lactobacillus crispatus
Gardnerella vaginalis
Epithelial barrier
Inflammation
TLR2
Online Access:https://doi.org/10.1186/s40168-022-01317-9

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