The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics
BackgroundPulse pressure (PP) may play a role in the development of cardiovascular disease, and the optimal PP for different ages and sexes is unknown. In a prospective cohort, we studied subjects with favorable cardiovascular health (CVH), proposed the mean PP as the optimal PP values, and demonstr...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.930443/full |
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| author | Chung-Hsing Chou Chung-Hsing Chou Jiu-Haw Yin Jiu-Haw Yin Yu-Kai Lin Yu-Kai Lin Fu-Chi Yang Ta-Wei Chu Ta-Wei Chu Yuan Chieh Chuang Chia Wen Lin Giia-Sheun Peng Giia-Sheun Peng Yueh-Feng Sung |
| author_facet | Chung-Hsing Chou Chung-Hsing Chou Jiu-Haw Yin Jiu-Haw Yin Yu-Kai Lin Yu-Kai Lin Fu-Chi Yang Ta-Wei Chu Ta-Wei Chu Yuan Chieh Chuang Chia Wen Lin Giia-Sheun Peng Giia-Sheun Peng Yueh-Feng Sung |
| author_sort | Chung-Hsing Chou |
| collection | DOAJ |
| description | BackgroundPulse pressure (PP) may play a role in the development of cardiovascular disease, and the optimal PP for different ages and sexes is unknown. In a prospective cohort, we studied subjects with favorable cardiovascular health (CVH), proposed the mean PP as the optimal PP values, and demonstrated its relationship with healthy lifestyles.Methods and resultsBetween 1996 and 2016, a total of 162,636 participants (aged 20 years or above; mean age 34.9 years; 26.4% male subjects; meeting criteria for favorable health) were recruited for a medical examination program. PP in male subjects was 45.6 ± 9.4 mmHg and increased after the age of 50 years. PP in female subjects was 41.8 ± 9.5 mmHg and increased after the age of 40 years, exceeding that of male subjects after the age of 50 years. Except for female subjects with a PP of 40–70 mmHg, PP increase correlates with both systolic blood pressure (BP) increase and diastolic BP decrease. Individuals with mean PP values are more likely to meet health metrics, including body mass index (BMI) <25 kg/m2 (chi-squared = 9.35, p<0.01 in male subjects; chi-squared = 208.79, p < 0.001 in female subjects) and BP <120/80 mmHg (chi-squared =1,300, p < 0.001 in male subjects; chi-squared =11,000, p < 0.001 in female subjects). We propose a health score (Hscore) based on the sum of five metrics (BP, BMI, being physically active, non-smoking, and healthy diet), which significantly correlates with the optimal PP.ConclusionThe mean PP (within ±1 standard deviation) could be proposed as the optimal PP in the adult population with favorable CVH. The relationship between health metrics and the optimal PP based on age and sex was further demonstrated to validate the Hscore. |
| first_indexed | 2024-04-12T03:51:37Z |
| format | Article |
| id | doaj.art-37c7e7276f224de2942804281337ea9e |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-12T03:51:37Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-37c7e7276f224de2942804281337ea9e2022-12-22T03:48:58ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-12-01910.3389/fcvm.2022.930443930443The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metricsChung-Hsing Chou0Chung-Hsing Chou1Jiu-Haw Yin2Jiu-Haw Yin3Yu-Kai Lin4Yu-Kai Lin5Fu-Chi Yang6Ta-Wei Chu7Ta-Wei Chu8Yuan Chieh Chuang9Chia Wen Lin10Giia-Sheun Peng11Giia-Sheun Peng12Yueh-Feng Sung13Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei, TaiwanDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDivision of Neurology, Department of Internal Medicine, Taipei Veterans General Hospital, Hsinchu, TaiwanDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei, TaiwanDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDepartment of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanMJ Health Screening Center, Taipei, TaiwanMJ Health Research Foundation, MJ Group, Taipei, TaiwanMJ Health Research Foundation, MJ Group, Taipei, TaiwanDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDivision of Neurology, Department of Internal Medicine, Taipei Veterans General Hospital, Hsinchu, TaiwanDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanBackgroundPulse pressure (PP) may play a role in the development of cardiovascular disease, and the optimal PP for different ages and sexes is unknown. In a prospective cohort, we studied subjects with favorable cardiovascular health (CVH), proposed the mean PP as the optimal PP values, and demonstrated its relationship with healthy lifestyles.Methods and resultsBetween 1996 and 2016, a total of 162,636 participants (aged 20 years or above; mean age 34.9 years; 26.4% male subjects; meeting criteria for favorable health) were recruited for a medical examination program. PP in male subjects was 45.6 ± 9.4 mmHg and increased after the age of 50 years. PP in female subjects was 41.8 ± 9.5 mmHg and increased after the age of 40 years, exceeding that of male subjects after the age of 50 years. Except for female subjects with a PP of 40–70 mmHg, PP increase correlates with both systolic blood pressure (BP) increase and diastolic BP decrease. Individuals with mean PP values are more likely to meet health metrics, including body mass index (BMI) <25 kg/m2 (chi-squared = 9.35, p<0.01 in male subjects; chi-squared = 208.79, p < 0.001 in female subjects) and BP <120/80 mmHg (chi-squared =1,300, p < 0.001 in male subjects; chi-squared =11,000, p < 0.001 in female subjects). We propose a health score (Hscore) based on the sum of five metrics (BP, BMI, being physically active, non-smoking, and healthy diet), which significantly correlates with the optimal PP.ConclusionThe mean PP (within ±1 standard deviation) could be proposed as the optimal PP in the adult population with favorable CVH. The relationship between health metrics and the optimal PP based on age and sex was further demonstrated to validate the Hscore.https://www.frontiersin.org/articles/10.3389/fcvm.2022.930443/fullpulse pressurearterial stiffnesscardiovascular diseasehealth metricshealth score |
| spellingShingle | Chung-Hsing Chou Chung-Hsing Chou Jiu-Haw Yin Jiu-Haw Yin Yu-Kai Lin Yu-Kai Lin Fu-Chi Yang Ta-Wei Chu Ta-Wei Chu Yuan Chieh Chuang Chia Wen Lin Giia-Sheun Peng Giia-Sheun Peng Yueh-Feng Sung The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics Frontiers in Cardiovascular Medicine pulse pressure arterial stiffness cardiovascular disease health metrics health score |
| title | The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics |
| title_full | The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics |
| title_fullStr | The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics |
| title_full_unstemmed | The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics |
| title_short | The optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics |
| title_sort | optimal pulse pressures for healthy adults with different ages and sexes correlate with cardiovascular health metrics |
| topic | pulse pressure arterial stiffness cardiovascular disease health metrics health score |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.930443/full |
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