TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis

Objective(s): Acute kidney injury (AKI) is a major component of isoproterenol (ISO) induced cardiorenal syndrome. In this study, we investigated the effect of TLR4‐IN‐C34 as a toll-like receptor (TLR)-4 inhibitor on ameliorating ISO-induced AKI and the possible molecular underlying pathways. Materia...

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Bibliographic Details
Main Authors: Hadeer Abdelsalam, Manar Helal, Nashwa Abu-Elsaad
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_21157_ce4a41b7831aa4ec8af6e22372edf164.pdf