Exogenous neural stem cell transplantation for cerebral ischemia
Cerebral ischemic injury is the main manifestation of stroke, and its incidence in stroke patients is 70–80%. Although ischemic stroke can be treated with tissue-type plasminogen activator, its time window of effectiveness is narrow. Therefore, the incidence of paralysis, hypoesthesia, aphasia, dysp...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Neural Regeneration Research |
| Subjects: | |
| Online Access: | http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1129;epage=1137;aulast=Liao |
| _version_ | 1818203400663203840 |
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| author | Ling-Yi Liao Benson Wui-Man Lau Dalinda Isabel Sánchez-Vidaña Qiang Gao |
| author_facet | Ling-Yi Liao Benson Wui-Man Lau Dalinda Isabel Sánchez-Vidaña Qiang Gao |
| author_sort | Ling-Yi Liao |
| collection | DOAJ |
| description | Cerebral ischemic injury is the main manifestation of stroke, and its incidence in stroke patients is 70–80%. Although ischemic stroke can be treated with tissue-type plasminogen activator, its time window of effectiveness is narrow. Therefore, the incidence of paralysis, hypoesthesia, aphasia, dysphagia, and cognitive impairment caused by cerebral ischemia is high. Nerve tissue regeneration can promote the recovery of the aforementioned dysfunction. Neural stem cells can participate in the reconstruction of the damaged nervous system and promote the recovery of nervous function during self-repair of damaged brain tissue. Neural stem cell transplantation for ischemic stroke has been a hot topic for more than 10 years. This review discusses the treatment of ischemic stroke with neural stem cells, as well as the mechanisms of their involvement in stroke treatment. |
| first_indexed | 2024-12-12T03:24:45Z |
| format | Article |
| id | doaj.art-37cde752974d4ef489a78860671dd90c |
| institution | Directory Open Access Journal |
| issn | 1673-5374 |
| language | English |
| last_indexed | 2024-12-12T03:24:45Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Neural Regeneration Research |
| spelling | doaj.art-37cde752974d4ef489a78860671dd90c2022-12-22T00:40:04ZengWolters Kluwer Medknow PublicationsNeural Regeneration Research1673-53742019-01-011471129113710.4103/1673-5374.251188Exogenous neural stem cell transplantation for cerebral ischemiaLing-Yi LiaoBenson Wui-Man LauDalinda Isabel Sánchez-VidañaQiang GaoCerebral ischemic injury is the main manifestation of stroke, and its incidence in stroke patients is 70–80%. Although ischemic stroke can be treated with tissue-type plasminogen activator, its time window of effectiveness is narrow. Therefore, the incidence of paralysis, hypoesthesia, aphasia, dysphagia, and cognitive impairment caused by cerebral ischemia is high. Nerve tissue regeneration can promote the recovery of the aforementioned dysfunction. Neural stem cells can participate in the reconstruction of the damaged nervous system and promote the recovery of nervous function during self-repair of damaged brain tissue. Neural stem cell transplantation for ischemic stroke has been a hot topic for more than 10 years. This review discusses the treatment of ischemic stroke with neural stem cells, as well as the mechanisms of their involvement in stroke treatment.http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1129;epage=1137;aulast=Liaonerve regeneration; stem cell therapy; neural stem cells; cell transplantation; ischemic stroke; cerebral ischemia; neuroplasticity; functional recovery; neural regeneration |
| spellingShingle | Ling-Yi Liao Benson Wui-Man Lau Dalinda Isabel Sánchez-Vidaña Qiang Gao Exogenous neural stem cell transplantation for cerebral ischemia Neural Regeneration Research nerve regeneration; stem cell therapy; neural stem cells; cell transplantation; ischemic stroke; cerebral ischemia; neuroplasticity; functional recovery; neural regeneration |
| title | Exogenous neural stem cell transplantation for cerebral ischemia |
| title_full | Exogenous neural stem cell transplantation for cerebral ischemia |
| title_fullStr | Exogenous neural stem cell transplantation for cerebral ischemia |
| title_full_unstemmed | Exogenous neural stem cell transplantation for cerebral ischemia |
| title_short | Exogenous neural stem cell transplantation for cerebral ischemia |
| title_sort | exogenous neural stem cell transplantation for cerebral ischemia |
| topic | nerve regeneration; stem cell therapy; neural stem cells; cell transplantation; ischemic stroke; cerebral ischemia; neuroplasticity; functional recovery; neural regeneration |
| url | http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1129;epage=1137;aulast=Liao |
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