Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT
Competitive endogenous RNAs help to regulate biological processes by regulating miRNA activity levels. Here the author show TGFBI acts as a ceRNA for miR-21 in the epithelial-to-mesenchymal transition.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-09649-1 |
| _version_ | 1818684793206865920 |
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| author | Yuwei Liu Mengzhu Xue Shaowei Du Wanwan Feng Ke Zhang Liwen Zhang Haiyue Liu Guoyi Jia Lingshuang Wu Xin Hu Luonan Chen Peng Wang |
| author_facet | Yuwei Liu Mengzhu Xue Shaowei Du Wanwan Feng Ke Zhang Liwen Zhang Haiyue Liu Guoyi Jia Lingshuang Wu Xin Hu Luonan Chen Peng Wang |
| author_sort | Yuwei Liu |
| collection | DOAJ |
| description | Competitive endogenous RNAs help to regulate biological processes by regulating miRNA activity levels. Here the author show TGFBI acts as a ceRNA for miR-21 in the epithelial-to-mesenchymal transition. |
| first_indexed | 2024-12-17T10:56:16Z |
| format | Article |
| id | doaj.art-37cec35022ef4202aeb390eea51f5157 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:56:16Z |
| publishDate | 2019-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-37cec35022ef4202aeb390eea51f51572022-12-21T21:51:48ZengNature PortfolioNature Communications2041-17232019-04-0110111210.1038/s41467-019-09649-1Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMTYuwei Liu0Mengzhu Xue1Shaowei Du2Wanwan Feng3Ke Zhang4Liwen Zhang5Haiyue Liu6Guoyi Jia7Lingshuang Wu8Xin Hu9Luonan Chen10Peng Wang11Laboratory of Systems Biology, Shanghai Advanced Research Institute, Chinese Academy of SciencesLaboratory of Systems Biology, Shanghai Advanced Research Institute, Chinese Academy of SciencesLaboratory of Systems Biology, Shanghai Advanced Research Institute, Chinese Academy of SciencesBio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of SciencesBio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of SciencesUniversity of Chinese Academy of SciencesLaboratory of Systems Biology, Shanghai Advanced Research Institute, Chinese Academy of SciencesLaboratory of Systems Biology, Shanghai Advanced Research Institute, Chinese Academy of SciencesSchool of Life Science and Technology, ShanghaiTech UniversityDepartment of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Fudan UniversityKey Laboratory of Systems Biology, Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of SciencesLaboratory of Systems Biology, Shanghai Advanced Research Institute, Chinese Academy of SciencesCompetitive endogenous RNAs help to regulate biological processes by regulating miRNA activity levels. Here the author show TGFBI acts as a ceRNA for miR-21 in the epithelial-to-mesenchymal transition.https://doi.org/10.1038/s41467-019-09649-1 |
| spellingShingle | Yuwei Liu Mengzhu Xue Shaowei Du Wanwan Feng Ke Zhang Liwen Zhang Haiyue Liu Guoyi Jia Lingshuang Wu Xin Hu Luonan Chen Peng Wang Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT Nature Communications |
| title | Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT |
| title_full | Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT |
| title_fullStr | Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT |
| title_full_unstemmed | Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT |
| title_short | Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT |
| title_sort | competitive endogenous rna is an intrinsic component of emt regulatory circuits and modulates emt |
| url | https://doi.org/10.1038/s41467-019-09649-1 |
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