Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case Report

Perioperative management of pheochromocytoma in the setting of catecholamine-induced heart failure requires careful consideration of hemodynamic optimization and possible mechanical circulatory support. A Jehovah’s Witness patient with catecholamine-induced acutely decompensated heart failure requir...

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Main Authors: Bachman Sarah A., Peterson Ryan S., Burrage Peter S., Hickerson Leigh C
Format: Article
Language:English
Published: Sciendo 2021-11-01
Series:The Journal of Critical Care Medicine
Subjects:
Online Access:https://doi.org/10.2478/jccm-2021-0038
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author Bachman Sarah A.
Peterson Ryan S.
Burrage Peter S.
Hickerson Leigh C
author_facet Bachman Sarah A.
Peterson Ryan S.
Burrage Peter S.
Hickerson Leigh C
author_sort Bachman Sarah A.
collection DOAJ
description Perioperative management of pheochromocytoma in the setting of catecholamine-induced heart failure requires careful consideration of hemodynamic optimization and possible mechanical circulatory support. A Jehovah’s Witness patient with catecholamine-induced acutely decompensated heart failure required dependable afterload reduction for a cardio-protective strategy. This was emphasized due to the relative contraindication to perioperative anticoagulation required for mechanical circulatory support. A phenylephrine challenge clearly demonstrated adequate alpha blockade after only 24 hours of phenoxybenzamine treatment. This resulted in advancement of the surgery date. This case also highlights management of beta blockade, volume and salt loading, autologous blood transfusion, and profound post-operative vasoplegia in the setting of cardiogenic shock. Careful attention to hemodynamic optimization and cardio-protective strategies ultimately resulted in positive outcome for this challenging clinical scenario.
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spelling doaj.art-37d804a30bcc43449e7796a84f81e7c92023-12-02T06:30:02ZengSciendoThe Journal of Critical Care Medicine2393-18172021-11-0181556010.2478/jccm-2021-0038Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case ReportBachman Sarah A.0Peterson Ryan S.1Burrage Peter S.2Hickerson Leigh C3Dartmouth-Hitchcock Medical Center, Lebanon, NH, USADartmouth-Hitchcock Medical Center, Lebanon, NH, USADartmouth-Hitchcock Medical Center, Lebanon, NH, USADartmouth-Hitchcock Medical Center, Lebanon, NH, USAPerioperative management of pheochromocytoma in the setting of catecholamine-induced heart failure requires careful consideration of hemodynamic optimization and possible mechanical circulatory support. A Jehovah’s Witness patient with catecholamine-induced acutely decompensated heart failure required dependable afterload reduction for a cardio-protective strategy. This was emphasized due to the relative contraindication to perioperative anticoagulation required for mechanical circulatory support. A phenylephrine challenge clearly demonstrated adequate alpha blockade after only 24 hours of phenoxybenzamine treatment. This resulted in advancement of the surgery date. This case also highlights management of beta blockade, volume and salt loading, autologous blood transfusion, and profound post-operative vasoplegia in the setting of cardiogenic shock. Careful attention to hemodynamic optimization and cardio-protective strategies ultimately resulted in positive outcome for this challenging clinical scenario.https://doi.org/10.2478/jccm-2021-0038pheochromocytomasystolic heart failurestress cardiomyopathyvasoplegiabloodless medical and surgical procedures
spellingShingle Bachman Sarah A.
Peterson Ryan S.
Burrage Peter S.
Hickerson Leigh C
Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case Report
The Journal of Critical Care Medicine
pheochromocytoma
systolic heart failure
stress cardiomyopathy
vasoplegia
bloodless medical and surgical procedures
title Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case Report
title_full Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case Report
title_fullStr Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case Report
title_full_unstemmed Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case Report
title_short Pheochromocytoma, Fulminant Heart Failure, and a Phenylephrine Challenge. The Perioperative Management of Adrenalectomy in a Jehovah’s Witness Patient: A Case Report
title_sort pheochromocytoma fulminant heart failure and a phenylephrine challenge the perioperative management of adrenalectomy in a jehovah s witness patient a case report
topic pheochromocytoma
systolic heart failure
stress cardiomyopathy
vasoplegia
bloodless medical and surgical procedures
url https://doi.org/10.2478/jccm-2021-0038
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