Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus
Objective: Cardiac Autonomic neuropathy is one of the complications in diabetic patients. This study intends to detect the prevalence of QTc prolongation in diabetic patients as well as its relationship with cardiac autonomic neuropathy. Materials & Methods: The present study was conducted...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Prathima Institute of Medical Sciences
2017-12-01
|
| Series: | Perspectives In Medical Research |
| Subjects: | |
| Online Access: | http://www.pimr.org.in/natarajan_vol5-issue3-2017.PDF |
| _version_ | 1797462368283787264 |
|---|---|
| author | N Natarajan1 , M S Ramaiyah2 |
| author_facet | N Natarajan1 , M S Ramaiyah2 |
| author_sort | N Natarajan1 , M S Ramaiyah2 |
| collection | DOAJ |
| description | Objective: Cardiac Autonomic neuropathy is one of the
complications in diabetic patients. This study intends to detect
the prevalence of QTc prolongation in diabetic patients as well
as its relationship with cardiac autonomic neuropathy.
Materials & Methods: The present study was
conducted on 50 diabetic patients. Cardiac autonomic
neuropathy was assessed by non-invasive tests: Deep breathing
test, Valsalva ratio ,Immediate heart rate response to standing
30:15,B.P rise with sustained hand grip and postural
hypotension. Scoring and grading were done for cardiac
autonomic neuropathy . Even QT interval and QTc interval were
determined.
Results: Out of 50 diabetic patients, 22(44%) were
males and 28 (56%) females. 26 patients (52%) having grade I
cardiac autonomic neuropathy had no prolonged QTc interval
. While, 24 patients (48%) had QTc prolonged were associated
with grade II, III and IV cardiac autonomic neuropathy. The
sensitivity and specificity of prolonged QTc were 46% and
100%, respectively.
Conclusion: QTc prolongation correlated positivity with
degree of cardiac autonomic neuropathy in diabetic patients |
| first_indexed | 2024-03-09T17:36:37Z |
| format | Article |
| id | doaj.art-37d8b567cc924b51b014942dc3f8204e |
| institution | Directory Open Access Journal |
| issn | 2348-1447 2348-229X |
| language | English |
| last_indexed | 2024-03-09T17:36:37Z |
| publishDate | 2017-12-01 |
| publisher | Prathima Institute of Medical Sciences |
| record_format | Article |
| series | Perspectives In Medical Research |
| spelling | doaj.art-37d8b567cc924b51b014942dc3f8204e2023-11-24T11:52:43ZengPrathima Institute of Medical SciencesPerspectives In Medical Research2348-14472348-229X2017-12-01536267Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitusN Natarajan1 , M S Ramaiyah20 Kerala Medical CollegeObjective: Cardiac Autonomic neuropathy is one of the complications in diabetic patients. This study intends to detect the prevalence of QTc prolongation in diabetic patients as well as its relationship with cardiac autonomic neuropathy. Materials & Methods: The present study was conducted on 50 diabetic patients. Cardiac autonomic neuropathy was assessed by non-invasive tests: Deep breathing test, Valsalva ratio ,Immediate heart rate response to standing 30:15,B.P rise with sustained hand grip and postural hypotension. Scoring and grading were done for cardiac autonomic neuropathy . Even QT interval and QTc interval were determined. Results: Out of 50 diabetic patients, 22(44%) were males and 28 (56%) females. 26 patients (52%) having grade I cardiac autonomic neuropathy had no prolonged QTc interval . While, 24 patients (48%) had QTc prolonged were associated with grade II, III and IV cardiac autonomic neuropathy. The sensitivity and specificity of prolonged QTc were 46% and 100%, respectively. Conclusion: QTc prolongation correlated positivity with degree of cardiac autonomic neuropathy in diabetic patientshttp://www.pimr.org.in/natarajan_vol5-issue3-2017.PDFdiabetes mellituscardiac autonomic neuropathyqtc interval |
| spellingShingle | N Natarajan1 , M S Ramaiyah2 Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus Perspectives In Medical Research diabetes mellitus cardiac autonomic neuropathy qtc interval |
| title | Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus |
| title_full | Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus |
| title_fullStr | Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus |
| title_full_unstemmed | Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus |
| title_short | Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus |
| title_sort | study of relationship between qtc prolongation and cardiac autonomic neuropathy in diabetes mellitus |
| topic | diabetes mellitus cardiac autonomic neuropathy qtc interval |
| url | http://www.pimr.org.in/natarajan_vol5-issue3-2017.PDF |
| work_keys_str_mv | AT nnatarajan1msramaiyah2 studyofrelationshipbetweenqtcprolongationandcardiacautonomicneuropathyindiabetesmellitus |