Sedation for adult ICU patients: A narrative review including a retrospective study of our own data

The optimization of patients' treatment in the intensive care unit (ICU) needs a lot of information and literature analysis. Many changes have been made in the last years to help evaluate sedated patients by scores to help take care of them. Patients were completely sedated and had continuous i...

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Main Authors: David De Bels, Ibrahim Bousbiat, Emily Perriens, Sydney Blackman, Patrick M Honoré
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Saudi Journal of Anaesthesia
Subjects:
Online Access:http://www.saudija.org/article.asp?issn=1658-354X;year=2023;volume=17;issue=2;spage=223;epage=235;aulast=Bels
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author David De Bels
Ibrahim Bousbiat
Emily Perriens
Sydney Blackman
Patrick M Honoré
author_facet David De Bels
Ibrahim Bousbiat
Emily Perriens
Sydney Blackman
Patrick M Honoré
author_sort David De Bels
collection DOAJ
description The optimization of patients' treatment in the intensive care unit (ICU) needs a lot of information and literature analysis. Many changes have been made in the last years to help evaluate sedated patients by scores to help take care of them. Patients were completely sedated and had continuous intravenous analgesia and neuromuscular blockades. These three drug classes were the main drugs used for intubated patients in the ICU. During these last 20 years, ICU management went from fully sedated to awake, calm, and nonagitated patients, using less sedatives and choosing other drugs to decrease the risks of delirium during or after the ICU stay. Thus, the usefulness of these three drug classes has been challenged. The analgesic drugs used were primarily opioids but the use of other drugs instead is increasing to lessen or wean the use of opioids. In severe acute respiratory distress syndrome patients, neuromuscular blocking agents have been used frequently to block spontaneous respiration for 48 hours or more; however, this has recently been abolished. Optimizing a patient's comfort during hemodynamic or respiratory extracorporeal support is essential to reduce toxicity and secondary complications.
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spelling doaj.art-37de43f389ea47ea9d553b0237d5e3352023-03-21T11:26:55ZengWolters Kluwer Medknow PublicationsSaudi Journal of Anaesthesia1658-354X2023-01-0117222323510.4103/sja.sja_905_22Sedation for adult ICU patients: A narrative review including a retrospective study of our own dataDavid De BelsIbrahim BousbiatEmily PerriensSydney BlackmanPatrick M HonoréThe optimization of patients' treatment in the intensive care unit (ICU) needs a lot of information and literature analysis. Many changes have been made in the last years to help evaluate sedated patients by scores to help take care of them. Patients were completely sedated and had continuous intravenous analgesia and neuromuscular blockades. These three drug classes were the main drugs used for intubated patients in the ICU. During these last 20 years, ICU management went from fully sedated to awake, calm, and nonagitated patients, using less sedatives and choosing other drugs to decrease the risks of delirium during or after the ICU stay. Thus, the usefulness of these three drug classes has been challenged. The analgesic drugs used were primarily opioids but the use of other drugs instead is increasing to lessen or wean the use of opioids. In severe acute respiratory distress syndrome patients, neuromuscular blocking agents have been used frequently to block spontaneous respiration for 48 hours or more; however, this has recently been abolished. Optimizing a patient's comfort during hemodynamic or respiratory extracorporeal support is essential to reduce toxicity and secondary complications.http://www.saudija.org/article.asp?issn=1658-354X;year=2023;volume=17;issue=2;spage=223;epage=235;aulast=Belsanalgesiabenzodiazepinesdeliriumdexmedetomidinemechanical ventilation opioids sedationneuromuscular blockadepainpropofol
spellingShingle David De Bels
Ibrahim Bousbiat
Emily Perriens
Sydney Blackman
Patrick M Honoré
Sedation for adult ICU patients: A narrative review including a retrospective study of our own data
Saudi Journal of Anaesthesia
analgesia
benzodiazepines
delirium
dexmedetomidine
mechanical ventilation opioids sedation
neuromuscular blockade
pain
propofol
title Sedation for adult ICU patients: A narrative review including a retrospective study of our own data
title_full Sedation for adult ICU patients: A narrative review including a retrospective study of our own data
title_fullStr Sedation for adult ICU patients: A narrative review including a retrospective study of our own data
title_full_unstemmed Sedation for adult ICU patients: A narrative review including a retrospective study of our own data
title_short Sedation for adult ICU patients: A narrative review including a retrospective study of our own data
title_sort sedation for adult icu patients a narrative review including a retrospective study of our own data
topic analgesia
benzodiazepines
delirium
dexmedetomidine
mechanical ventilation opioids sedation
neuromuscular blockade
pain
propofol
url http://www.saudija.org/article.asp?issn=1658-354X;year=2023;volume=17;issue=2;spage=223;epage=235;aulast=Bels
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AT emilyperriens sedationforadulticupatientsanarrativereviewincludingaretrospectivestudyofourowndata
AT sydneyblackman sedationforadulticupatientsanarrativereviewincludingaretrospectivestudyofourowndata
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