A20 Enhances the Expression of the Proto-Oncogene C-Myc by Downregulating TRAF6 Ubiquitination after ALV-A Infection

A20 Enhances the Expression of the Proto-Oncogene C-Myc by Downregulating TRAF6 Ubiquitination after ALV-A Infection

Hens infected with avian leukosis virus subgroup A (ALV-A) experience stunted growth, immunosuppression, and potentially, lymphoma development. According to past research, A20 can both promote and inhibit tumor growth. In this study, DF-1 cells were infected with ALV-A rHB2015012, and Gp85 expressio...

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Bibliographic Details
Main Authors: Xueyang Chen, Xingming Wang, Yuxin Yang, Chun Fang, Jing Liu, Xiongyan Liang, Yuying Yang
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
ALV-A
chicken A20
TRAF6
STAT3
c-myc
tumorigenic mechanism
Online Access:https://www.mdpi.com/1999-4915/14/10/2210

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