GDF-5 promotes epidermal stem cells proliferation via Foxg1-cyclin D1 signaling

GDF-5 promotes epidermal stem cells proliferation via Foxg1-cyclin D1 signaling

Abstract Objective Epidermal stem cells (EpSCs) can self-renew, which are responsible for the long-term maintenance of the skin, and it also plays a critical role in wound re-epithelization, but the mechanism underlying EpSCs proliferation is unclear. GDF-5, also known as BMP-14, is a member of the...

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Bibliographic Details
Main Authors: Xiaohong Zhao, Ruyu Bian, Fan Wang, Ying Wang, Xue Li, Yicheng Guo, Xiaorong Zhang, Gaoxing Luo, Rixing Zhan
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
GDF-5
Mouse epidermal stem cells
Foxg1
Cell proliferation
Cyclin D1
Online Access:https://doi.org/10.1186/s13287-020-02106-7

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