Genes encoding two Theileria parva antigens recognized by CD8+ T-cells exhibit sequence diversity in South Sudanese cattle populations but the majority of alleles are similar to the Muguga component of the live vaccine cocktail.
East Coast fever (ECF), caused by Theileria parva infection, is a frequently fatal disease of cattle in eastern, central and southern Africa, and an emerging disease in South Sudan. Immunization using the infection and treatment method (ITM) is increasingly being used for control in countries affect...
Main Authors: | Diaeldin A Salih, Roger Pelle, Joram M Mwacharo, Moses N Njahira, Wani L Marcellino, Henry Kiara, Agol K Malak, Abdel Rahim M El Hussein, Richard Bishop, Robert A Skilton |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5322890?pdf=render |
Similar Items
-
Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals
by: Lucilla Steinaa, et al.
Published: (2018-05-01) -
Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes.
by: Graham, S, et al.
Published: (2006) -
Population Genetic Analysis and Sub-Structuring of Theileria annulata in Sudan
by: Diaeldin A. Salih, et al.
Published: (2021-11-01) -
Lack of evidence for safe vaccination with the Muguga cocktail in Sudan
by: Dirk Geysen, et al.
Published: (2013-03-01) -
Characterization of the Theileria parva sporozoite proteome.
by: Nyagwange, J, et al.
Published: (2017)