A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVES

Around the world, the use of dietary supplements is common and can be purchased without consulting a doctor. It is believed that more than 50 % of adults worldwide use dietary supplements. The article deals with the regulation of the market of biologically active additives worldwide, including the R...

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Main Authors: M. L. Maksimov, S. A. Simakova
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-06-01
Series:Безопасность и риск фармакотерапии
Subjects:
Online Access:https://www.risksafety.ru/jour/article/view/103
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author M. L. Maksimov
S. A. Simakova
author_facet M. L. Maksimov
S. A. Simakova
author_sort M. L. Maksimov
collection DOAJ
description Around the world, the use of dietary supplements is common and can be purchased without consulting a doctor. It is believed that more than 50 % of adults worldwide use dietary supplements. The article deals with the regulation of the market of biologically active additives worldwide, including the Russian Federation, the safety of use, the development of undesirable reactions. Information was searched on databases on the development of medicinal liver damage associated with the use of biologically active additives containing green tea extract, usninic acid, 1,3-dimethylamylamine, vitamin A, anabolic androgenic steroids, linoleic acid, ephedra, Garcinia Cambogia used for weight loss. The use of anabolic steroids has revealed an increased risk of adverse reactions from the liver, cardiovascular and endocrine systems. The use of dietary supplements containing green tea extract can lead to severe liver damage. Analysis of adverse reactions after the use of dietary supplements under the trade name Herbalife revealed cases of falsification of drugs. The use of drugs containing vitamin a in high doses, ephedra, Garcinia Cambogia led to increased hepatic transaminases, mental disorders, osteoporosis, anorexia.
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spelling doaj.art-37e95b97c0fb4f0dbc28c97bfda933b62025-03-02T10:50:03ZrusMinistry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Безопасность и риск фармакотерапии2312-78212619-11642018-06-0162687710.30895/2312-7821-2018-6-2-68-77103A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVESM. L. Maksimov0S. A. Simakova1Kazan State Medical Academy — Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Healthcare of the Russian Federation; Scientific Centre for Expert Evaluation of Medicinal ProductsKazan State Medical Academy — Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Healthcare of the Russian FederationAround the world, the use of dietary supplements is common and can be purchased without consulting a doctor. It is believed that more than 50 % of adults worldwide use dietary supplements. The article deals with the regulation of the market of biologically active additives worldwide, including the Russian Federation, the safety of use, the development of undesirable reactions. Information was searched on databases on the development of medicinal liver damage associated with the use of biologically active additives containing green tea extract, usninic acid, 1,3-dimethylamylamine, vitamin A, anabolic androgenic steroids, linoleic acid, ephedra, Garcinia Cambogia used for weight loss. The use of anabolic steroids has revealed an increased risk of adverse reactions from the liver, cardiovascular and endocrine systems. The use of dietary supplements containing green tea extract can lead to severe liver damage. Analysis of adverse reactions after the use of dietary supplements under the trade name Herbalife revealed cases of falsification of drugs. The use of drugs containing vitamin a in high doses, ephedra, Garcinia Cambogia led to increased hepatic transaminases, mental disorders, osteoporosis, anorexia.https://www.risksafety.ru/jour/article/view/103words: dietary supplementshepatotoxicityadverse reactionsanabolic steroidsephedr
spellingShingle M. L. Maksimov
S. A. Simakova
A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVES
Безопасность и риск фармакотерапии
words: dietary supplements
hepatotoxicity
adverse reactions
anabolic steroids
ephedr
title A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVES
title_full A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVES
title_fullStr A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVES
title_full_unstemmed A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVES
title_short A REVIEW OF CASES OF DEVELOPMENT OF ACUTE HEPATIC INSUFFICIENCY DUE TO THE INTAKE OF BIOLOGICALLY ACTIVE ADDITIVES
title_sort review of cases of development of acute hepatic insufficiency due to the intake of biologically active additives
topic words: dietary supplements
hepatotoxicity
adverse reactions
anabolic steroids
ephedr
url https://www.risksafety.ru/jour/article/view/103
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