Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps Consistency

Deep learning methods provide significant assistance in analyzing coronavirus disease (COVID-19) in chest computed tomography (CT) images, including identification, severity assessment, and segmentation. Although the earlier developed methods address the lack of data and specific annotations, the cu...

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Main Authors: Stanislav Shimovolos, Andrey Shushko, Mikhail Belyaev, Boris Shirokikh
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Journal of Imaging
Subjects:
Online Access:https://www.mdpi.com/2313-433X/8/9/234
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author Stanislav Shimovolos
Andrey Shushko
Mikhail Belyaev
Boris Shirokikh
author_facet Stanislav Shimovolos
Andrey Shushko
Mikhail Belyaev
Boris Shirokikh
author_sort Stanislav Shimovolos
collection DOAJ
description Deep learning methods provide significant assistance in analyzing coronavirus disease (COVID-19) in chest computed tomography (CT) images, including identification, severity assessment, and segmentation. Although the earlier developed methods address the lack of data and specific annotations, the current goal is to build a robust algorithm for clinical use, having a larger pool of available data. With the larger datasets, the domain shift problem arises, affecting the performance of methods on the unseen data. One of the critical sources of domain shift in CT images is the difference in reconstruction kernels used to generate images from the raw data (sinograms). In this paper, we show a decrease in the COVID-19 segmentation quality of the model trained on the smooth and tested on the sharp reconstruction kernels. Furthermore, we compare several domain adaptation approaches to tackle the problem, such as task-specific augmentation and unsupervised adversarial learning. Finally, we propose the unsupervised adaptation method, called F-Consistency, that outperforms the previous approaches. Our method exploits a set of unlabeled CT image pairs which differ only in reconstruction kernels within every pair. It enforces the similarity of the network’s hidden representations (feature maps) by minimizing the mean squared error (MSE) between paired feature maps. We show our method achieving a 0.64 Dice Score on the test dataset with unseen sharp kernels, compared to the 0.56 Dice Score of the baseline model. Moreover, F-Consistency scores 0.80 Dice Score between predictions on the paired images, which almost doubles the baseline score of 0.46 and surpasses the other methods. We also show F-Consistency to better generalize on the unseen kernels and without the presence of the COVID-19 lesions than the other methods trained on unlabeled data.
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spelling doaj.art-37eac7ab297746fcad789009ba1180ba2023-11-23T17:04:32ZengMDPI AGJournal of Imaging2313-433X2022-08-018923410.3390/jimaging8090234Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps ConsistencyStanislav Shimovolos0Andrey Shushko1Mikhail Belyaev2Boris Shirokikh3Moscow Institute of Physics and Technology, 141701 Moscow, RussiaMoscow Institute of Physics and Technology, 141701 Moscow, RussiaSkolkovo Institute of Science and Technology, 143026 Moscow, RussiaSkolkovo Institute of Science and Technology, 143026 Moscow, RussiaDeep learning methods provide significant assistance in analyzing coronavirus disease (COVID-19) in chest computed tomography (CT) images, including identification, severity assessment, and segmentation. Although the earlier developed methods address the lack of data and specific annotations, the current goal is to build a robust algorithm for clinical use, having a larger pool of available data. With the larger datasets, the domain shift problem arises, affecting the performance of methods on the unseen data. One of the critical sources of domain shift in CT images is the difference in reconstruction kernels used to generate images from the raw data (sinograms). In this paper, we show a decrease in the COVID-19 segmentation quality of the model trained on the smooth and tested on the sharp reconstruction kernels. Furthermore, we compare several domain adaptation approaches to tackle the problem, such as task-specific augmentation and unsupervised adversarial learning. Finally, we propose the unsupervised adaptation method, called F-Consistency, that outperforms the previous approaches. Our method exploits a set of unlabeled CT image pairs which differ only in reconstruction kernels within every pair. It enforces the similarity of the network’s hidden representations (feature maps) by minimizing the mean squared error (MSE) between paired feature maps. We show our method achieving a 0.64 Dice Score on the test dataset with unseen sharp kernels, compared to the 0.56 Dice Score of the baseline model. Moreover, F-Consistency scores 0.80 Dice Score between predictions on the paired images, which almost doubles the baseline score of 0.46 and surpasses the other methods. We also show F-Consistency to better generalize on the unseen kernels and without the presence of the COVID-19 lesions than the other methods trained on unlabeled data.https://www.mdpi.com/2313-433X/8/9/234chest computed tomographyconvolutional neural networkCOVID-19 segmentationdomain adaptation
spellingShingle Stanislav Shimovolos
Andrey Shushko
Mikhail Belyaev
Boris Shirokikh
Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps Consistency
Journal of Imaging
chest computed tomography
convolutional neural network
COVID-19 segmentation
domain adaptation
title Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps Consistency
title_full Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps Consistency
title_fullStr Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps Consistency
title_full_unstemmed Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps Consistency
title_short Adaptation to CT Reconstruction Kernels by Enforcing Cross-Domain Feature Maps Consistency
title_sort adaptation to ct reconstruction kernels by enforcing cross domain feature maps consistency
topic chest computed tomography
convolutional neural network
COVID-19 segmentation
domain adaptation
url https://www.mdpi.com/2313-433X/8/9/234
work_keys_str_mv AT stanislavshimovolos adaptationtoctreconstructionkernelsbyenforcingcrossdomainfeaturemapsconsistency
AT andreyshushko adaptationtoctreconstructionkernelsbyenforcingcrossdomainfeaturemapsconsistency
AT mikhailbelyaev adaptationtoctreconstructionkernelsbyenforcingcrossdomainfeaturemapsconsistency
AT borisshirokikh adaptationtoctreconstructionkernelsbyenforcingcrossdomainfeaturemapsconsistency