A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India

Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones.Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution.Results: An isolate of Salmonella ente...

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Main Author: Belgode Narasimha Harish1, Godfred Antony Menezes1, Kengamuthu Sarangapani2, Subhash Chandra Parija1
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2008-08-01
Series:Journal of Infection in Developing Countries
Subjects:
Online Access:http://www.jidc.org/issn1972-2680/current-issue/68-vol-2-no-4-august-2008/168-a-case-report-and-review-of-the-literature-ciprofloxacin-resistant-salmonella-enterica-serovar-typhi-in-india
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author Belgode Narasimha Harish1, Godfred Antony Menezes1, Kengamuthu Sarangapani2, Subhash Chandra Parija1
author_facet Belgode Narasimha Harish1, Godfred Antony Menezes1, Kengamuthu Sarangapani2, Subhash Chandra Parija1
author_sort Belgode Narasimha Harish1, Godfred Antony Menezes1, Kengamuthu Sarangapani2, Subhash Chandra Parija1
collection DOAJ
description Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones.Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution.Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64µg/ml.Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxzone.
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spelling doaj.art-37eb63bd81a24b4b905365f813e1a5792022-12-22T03:54:57ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802008-08-0124324327A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in IndiaBelgode Narasimha Harish1, Godfred Antony Menezes1, Kengamuthu Sarangapani2, Subhash Chandra Parija1Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones.Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution.Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64µg/ml.Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxzone.http://www.jidc.org/issn1972-2680/current-issue/68-vol-2-no-4-august-2008/168-a-case-report-and-review-of-the-literature-ciprofloxacin-resistant-salmonella-enterica-serovar-typhi-in-indiaEnteric feverSalmonella Typhidrug resistance
spellingShingle Belgode Narasimha Harish1, Godfred Antony Menezes1, Kengamuthu Sarangapani2, Subhash Chandra Parija1
A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
Journal of Infection in Developing Countries
Enteric fever
Salmonella Typhi
drug resistance
title A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_full A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_fullStr A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_full_unstemmed A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_short A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_sort case report and review of the literature ciprofloxacin resistant salmonella enterica serovar typhi in india
topic Enteric fever
Salmonella Typhi
drug resistance
url http://www.jidc.org/issn1972-2680/current-issue/68-vol-2-no-4-august-2008/168-a-case-report-and-review-of-the-literature-ciprofloxacin-resistant-salmonella-enterica-serovar-typhi-in-india
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