Bone mesenchymal stem cell-derived exosomes prevent hyperoxia-induced apoptosis of primary type II alveolar epithelial cells in vitro

Bone mesenchymal stem cell-derived exosomes prevent hyperoxia-induced apoptosis of primary type II alveolar epithelial cells in vitro

Background The presence of alveolar epithelial type II cells (AECIIs) is one of the most important causes of bronchopulmonary dysplasia (BPD). Exosomes from bone mesenchymal stem cells (BMSCs) can reduce hyperoxia-induced damage and provide better results in terms of alveolar and pulmonary vasculari...

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Bibliographic Details
Main Authors: Wei Yang, Chao Huang, Wenjian Wang, Baozhu Zhang, Yunbin Chen, Xinlin Xie
Format: Article
Language:English
Published: PeerJ Inc. 2022-09-01
Series:PeerJ
Subjects:
Hyperoxia
Exosome
AECIIs
LY294002
Rapamycin
PI3K/Akt/mTOR/Ki67
Online Access:https://peerj.com/articles/13692.pdf

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