Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique
Terahertz time-domain spectroscopy (THz-TDS) is an effective coherent detection technique for deeply understanding the structures and functions of biomolecules. However, generally not full information in the whole THz range can be obtained due to the limited detection bandwidth (usually less than 5...
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MDPI AG
2019-03-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/19/5/1148 |
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| author | Miao Yu Shihan Yan Yong-qiang Sun Wang Sheng Fu Tang Xiao-yu Peng Yuan Hu |
| author_facet | Miao Yu Shihan Yan Yong-qiang Sun Wang Sheng Fu Tang Xiao-yu Peng Yuan Hu |
| author_sort | Miao Yu |
| collection | DOAJ |
| description | Terahertz time-domain spectroscopy (THz-TDS) is an effective coherent detection technique for deeply understanding the structures and functions of biomolecules. However, generally not full information in the whole THz range can be obtained due to the limited detection bandwidth (usually less than 5 THz) of the traditional THz-TDS systems. In this paper, effective THz absorption spectra in 0.5–10 THz range of five typical nucleobases of DNA/RNA are characterized with a super broadband THz detection technique, called the air-biased- coherent-detection (THz-ABCD) technique. Few unexpected characteristic absorption peaks appeared in the low-frequency region and meanwhile a series of anticipated characteristic absorption peaks are found in the high-frequency region. The fingerprint spectra of these nucleobases are helpful for further analysis on the vibration and twisting behavior of hydrogen bonds, van der Waals and electrostatic forces etc. between and within DNA/RNA biomolecules. |
| first_indexed | 2024-04-14T01:17:48Z |
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| id | doaj.art-37ee095f7f53445f8a271eacd9b647e0 |
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| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-14T01:17:48Z |
| publishDate | 2019-03-01 |
| publisher | MDPI AG |
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| series | Sensors |
| spelling | doaj.art-37ee095f7f53445f8a271eacd9b647e02022-12-22T02:20:46ZengMDPI AGSensors1424-82202019-03-01195114810.3390/s19051148s19051148Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection TechniqueMiao Yu0Shihan Yan1Yong-qiang Sun2Wang Sheng3Fu Tang4Xiao-yu Peng5Yuan Hu6Key Laboratory of Opto-electronic Measurement and Optical Information Transmission Technology, Ministry of Education, Changchun University of Science and Technology, Changchun 130022, ChinaChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Center of Applied Physics, Chongqing 400714, ChinaKey Laboratory of Opto-electronic Measurement and Optical Information Transmission Technology, Ministry of Education, Changchun University of Science and Technology, Changchun 130022, ChinaChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Terahertz Technology Research Center, Chongqing 400714, ChinaChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Terahertz Technology Research Center, Chongqing 400714, ChinaChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Terahertz Technology Research Center, Chongqing 400714, ChinaKey Laboratory of Opto-electronic Measurement and Optical Information Transmission Technology, Ministry of Education, Changchun University of Science and Technology, Changchun 130022, ChinaTerahertz time-domain spectroscopy (THz-TDS) is an effective coherent detection technique for deeply understanding the structures and functions of biomolecules. However, generally not full information in the whole THz range can be obtained due to the limited detection bandwidth (usually less than 5 THz) of the traditional THz-TDS systems. In this paper, effective THz absorption spectra in 0.5–10 THz range of five typical nucleobases of DNA/RNA are characterized with a super broadband THz detection technique, called the air-biased- coherent-detection (THz-ABCD) technique. Few unexpected characteristic absorption peaks appeared in the low-frequency region and meanwhile a series of anticipated characteristic absorption peaks are found in the high-frequency region. The fingerprint spectra of these nucleobases are helpful for further analysis on the vibration and twisting behavior of hydrogen bonds, van der Waals and electrostatic forces etc. between and within DNA/RNA biomolecules.http://www.mdpi.com/1424-8220/19/5/1148THz-TDSTHz-ABCD systemfingerprint spectrumnucleobase |
| spellingShingle | Miao Yu Shihan Yan Yong-qiang Sun Wang Sheng Fu Tang Xiao-yu Peng Yuan Hu Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique Sensors THz-TDS THz-ABCD system fingerprint spectrum nucleobase |
| title | Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique |
| title_full | Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique |
| title_fullStr | Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique |
| title_full_unstemmed | Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique |
| title_short | Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique |
| title_sort | characterization of nucleobases in broadband terahertz spectra from 0 5 to 10 thz with the air biased coherent detection technique |
| topic | THz-TDS THz-ABCD system fingerprint spectrum nucleobase |
| url | http://www.mdpi.com/1424-8220/19/5/1148 |
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