The impact of primary total hip and knee replacement on frailty: an observational prospective analysis
Abstract Background Osteoarthritis is a prevalent condition in frail older adults that requires hip or knee replacement in many patients. The aim of the study was to determine the impact of hip and knee arthroplasty on frailty. Methods In this prospective short-term study, we used data from 101 part...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12891-024-07210-w |
| _version_ | 1797350188863455232 |
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| author | Tobias Kappenschneider Philip Bammert Günther Maderbacher Felix Greimel Lukas Parik Dominik Emanuel Holzapfel Amadeus Dominik Schraag Julia Götz Katrin Michalk Joachim Grifka Matthias Meyer |
| author_facet | Tobias Kappenschneider Philip Bammert Günther Maderbacher Felix Greimel Lukas Parik Dominik Emanuel Holzapfel Amadeus Dominik Schraag Julia Götz Katrin Michalk Joachim Grifka Matthias Meyer |
| author_sort | Tobias Kappenschneider |
| collection | DOAJ |
| description | Abstract Background Osteoarthritis is a prevalent condition in frail older adults that requires hip or knee replacement in many patients. The aim of the study was to determine the impact of hip and knee arthroplasty on frailty. Methods In this prospective short-term study, we used data from 101 participants of the ongoing Special Orthopaedic Geriatrics (SOG) trial, funded by the German Federal Joint Committee (GBA). Frailty, measured by Fried’s Physical Frailty Phenotype (PFP), was assessed preoperatively, 7 days postoperatively, 4–6 weeks and 3 months after hip and knee arthroplasty. ANOVA with repeated measures and post-hoc tests for the subgroups were used for the statistical analysis. Results Of the 101 participants, 50 were pre-frail (1–2 PFP criteria) and 51 were frail (≥ 3 PFP criteria) preoperatively. In the pre-frail group, the PFP score decreased from 1.56 ± 0.50 (median 2) preoperatively to 0.53 ± 0.73 (median 0) 3 months after surgery (p < 0.001). The PFP score in the frail cohort decreased from 3.39 ± 1.45 (median 3) preoperatively to 1.27 ± 1.14 (median 1) 3 months postoperatively (p < 0.001). While the PFP score of the pre-frail participants increased 7 days after surgery, the PFP score of the frail group decreased significantly. Conclusion Pre-frail individuals often regain robustness and patients with frailty are no longer assessed as frail after surgery. Joint replacement is an effective intervention to improve frailty in hip and knee osteoarthritis. Trial registration This study is part of the Special Orthopaedic Geriatrics (SOG) trial, German Clinical Trials Register DRKS00024102. Registered on 19 January 2021. |
| first_indexed | 2024-03-08T12:41:10Z |
| format | Article |
| id | doaj.art-37f1072b6b734366ab84a9de221b0515 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-03-08T12:41:10Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-37f1072b6b734366ab84a9de221b05152024-01-21T12:07:11ZengBMCBMC Musculoskeletal Disorders1471-24742024-01-0125111110.1186/s12891-024-07210-wThe impact of primary total hip and knee replacement on frailty: an observational prospective analysisTobias Kappenschneider0Philip Bammert1Günther Maderbacher2Felix Greimel3Lukas Parik4Dominik Emanuel Holzapfel5Amadeus Dominik Schraag6Julia Götz7Katrin Michalk8Joachim Grifka9Matthias Meyer10Department of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Health Economics, Technical University of MunichDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterDepartment of Orthopaedic Surgery, Regensburg University Medical CenterAbstract Background Osteoarthritis is a prevalent condition in frail older adults that requires hip or knee replacement in many patients. The aim of the study was to determine the impact of hip and knee arthroplasty on frailty. Methods In this prospective short-term study, we used data from 101 participants of the ongoing Special Orthopaedic Geriatrics (SOG) trial, funded by the German Federal Joint Committee (GBA). Frailty, measured by Fried’s Physical Frailty Phenotype (PFP), was assessed preoperatively, 7 days postoperatively, 4–6 weeks and 3 months after hip and knee arthroplasty. ANOVA with repeated measures and post-hoc tests for the subgroups were used for the statistical analysis. Results Of the 101 participants, 50 were pre-frail (1–2 PFP criteria) and 51 were frail (≥ 3 PFP criteria) preoperatively. In the pre-frail group, the PFP score decreased from 1.56 ± 0.50 (median 2) preoperatively to 0.53 ± 0.73 (median 0) 3 months after surgery (p < 0.001). The PFP score in the frail cohort decreased from 3.39 ± 1.45 (median 3) preoperatively to 1.27 ± 1.14 (median 1) 3 months postoperatively (p < 0.001). While the PFP score of the pre-frail participants increased 7 days after surgery, the PFP score of the frail group decreased significantly. Conclusion Pre-frail individuals often regain robustness and patients with frailty are no longer assessed as frail after surgery. Joint replacement is an effective intervention to improve frailty in hip and knee osteoarthritis. Trial registration This study is part of the Special Orthopaedic Geriatrics (SOG) trial, German Clinical Trials Register DRKS00024102. Registered on 19 January 2021.https://doi.org/10.1186/s12891-024-07210-wOrthogeriatricFrailtyHip arthroplastyKnee arthroplastyOlder people |
| spellingShingle | Tobias Kappenschneider Philip Bammert Günther Maderbacher Felix Greimel Lukas Parik Dominik Emanuel Holzapfel Amadeus Dominik Schraag Julia Götz Katrin Michalk Joachim Grifka Matthias Meyer The impact of primary total hip and knee replacement on frailty: an observational prospective analysis BMC Musculoskeletal Disorders Orthogeriatric Frailty Hip arthroplasty Knee arthroplasty Older people |
| title | The impact of primary total hip and knee replacement on frailty: an observational prospective analysis |
| title_full | The impact of primary total hip and knee replacement on frailty: an observational prospective analysis |
| title_fullStr | The impact of primary total hip and knee replacement on frailty: an observational prospective analysis |
| title_full_unstemmed | The impact of primary total hip and knee replacement on frailty: an observational prospective analysis |
| title_short | The impact of primary total hip and knee replacement on frailty: an observational prospective analysis |
| title_sort | impact of primary total hip and knee replacement on frailty an observational prospective analysis |
| topic | Orthogeriatric Frailty Hip arthroplasty Knee arthroplasty Older people |
| url | https://doi.org/10.1186/s12891-024-07210-w |
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