Both ANT and ATPase are essential for mitochondrial permeability transition but not depolarization
Summary: An increase in permeability of the mitochondrial inner membrane, mitochondrial permeability transition (PT), is the central event responsible for cell death and tissue damage in conditions such as stroke and heart attack. PT is caused by the cyclosporin A (CSA)-dependent calcium-induced por...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-11-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222017199 |