Both ANT and ATPase are essential for mitochondrial permeability transition but not depolarization

Summary: An increase in permeability of the mitochondrial inner membrane, mitochondrial permeability transition (PT), is the central event responsible for cell death and tissue damage in conditions such as stroke and heart attack. PT is caused by the cyclosporin A (CSA)-dependent calcium-induced por...

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Bibliographic Details
Main Authors: M.A. Neginskaya, S.E. Morris, E.V. Pavlov
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222017199