Fat body phospholipid state dictates hunger-driven feeding behavior

Fat body phospholipid state dictates hunger-driven feeding behavior

Diet-induced obesity leads to dysfunctional feeding behavior. However, the precise molecular nodes underlying diet-induced feeding motivation dysregulation are poorly understood. The fruit fly is a simple genetic model system yet displays significant evolutionary conservation to mammalian nutrient s...

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Bibliographic Details
Main Authors: Kevin P Kelly, Mroj Alassaf, Camille E Sullivan, Ava E Brent, Zachary H Goldberg, Michelle E Poling, Julien Dubrulle, Akhila Rajan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
PECT
homeostasis
obesity
insulin resistance
apolipoproteins
Drosophila
Online Access:https://elifesciences.org/articles/80282

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