Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer’s disease mice model

Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer’s disease mice model

<p>Abstract</p> <p>Background</p> <p>Alzheimer’s disease (AD) is pathologically characterized by excessive accumulation of amyloid-beta (Aβ) fibrils within the brain and activation of astrocytes and microglial cells. In this study, we examined anti-inflammatory and anti...

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Bibliographic Details
Main Authors:	Jin Peng, Kim Jin-A, Choi Dong-Young, Lee Young-Jung, Jung Heon Sang, Hong Jin Tae
Format:	Article
Language:	English
Published:	BMC 2013-01-01
Series:	Journal of Neuroinflammation
Subjects:	Alzheimer’s disease Amyloid-beta NF-κB STAT1/3 2,4-bis(p-hydroxyphenyl)-2-butenal
Online Access:	http://www.jneuroinflammation.com/content/10/1/2

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