Enhanced Oral Bioavailability of the Pharmacologically Active Lignin Magnolol via Zr-Based Metal Organic Framework Impregnation

Enhanced Oral Bioavailability of the Pharmacologically Active Lignin Magnolol via Zr-Based Metal Organic Framework Impregnation

Bioavailability plays an important role in drug activity in the human body, as certain drug amounts should be present to elicit activity. However, low bioavailability of drugs leads to negligible use for human benefit. In this study, the diversely active neolignan, magnolol, was impregnated onto a Z...

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Bibliographic Details
Main Authors: Joshua H. Santos, Mark Tristan J. Quimque, Allan Patrick G. Macabeo, Mary Jho-Anne T. Corpuz, Yun-Ming Wang, Tsai-Te Lu, Chia-Her Lin, Oliver B. Villaflores
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pharmaceutics
Subjects:
magnolol
metal organic framework
bioavailability
toxicity
Uio-66(Zr)
Online Access:https://www.mdpi.com/1999-4923/12/5/437

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