Minimal clinically important difference: The basics
This article is part of a collaborative methodological series of narrative reviews on biostatistics and clinical epidemiology. This review aims to present basic concepts about the minimal clinically important difference and its use in the field of clinical research and evidence synthesis. The minima...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Medwave Estudios Limitada
2021-04-01
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| Series: | Medwave |
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| Online Access: | https://www.medwave.cl/link.cgi/Medwave/Revisiones/MetodInvestReport/8149.act |
| _version_ | 1818650945032028160 |
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| author | Julieta Aldana Salas Apaza Juan Víctor Ariel Franco Nicolás Meza Eva Madrid Cristobal Loézar Luis Garegnani |
| author_facet | Julieta Aldana Salas Apaza Juan Víctor Ariel Franco Nicolás Meza Eva Madrid Cristobal Loézar Luis Garegnani |
| author_sort | Julieta Aldana Salas Apaza |
| collection | DOAJ |
| description | This article is part of a collaborative methodological series of narrative reviews on biostatistics and clinical epidemiology. This review aims to present basic concepts about the minimal clinically important difference and its use in the field of clinical research and evidence synthesis. The minimal clinically important difference is defined as the smallest difference in score in any domain or outcome of interest that patients can perceive as beneficial. It is a useful concept in several aspects since it links the magnitude of change with treatment decisions in clinical practice and emphasizes the primacy of the patient’s perception, affected by endless variables such as time, place, and current state of health, all of which can cause significant variability in results. |
| first_indexed | 2024-12-17T01:58:16Z |
| format | Article |
| id | doaj.art-380272b9f7944dac9b6eb3c12b54f9c9 |
| institution | Directory Open Access Journal |
| issn | 0717-6384 0717-6384 |
| language | English |
| last_indexed | 2024-12-17T01:58:16Z |
| publishDate | 2021-04-01 |
| publisher | Medwave Estudios Limitada |
| record_format | Article |
| series | Medwave |
| spelling | doaj.art-380272b9f7944dac9b6eb3c12b54f9c92022-12-21T22:07:53ZengMedwave Estudios LimitadaMedwave0717-63840717-63842021-04-012103e8149e814910.5867/medwave.2021.03.8149Minimal clinically important difference: The basicsJulieta Aldana Salas Apaza0Juan Víctor Ariel Franco1Nicolás Meza2Eva Madrid3Cristobal Loézar4Luis Garegnani5Universidad Nacional de La Matanza, Buenos Aires, ArgentinaInstituto Universitario Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, ArgentinaCentro Interdisciplinario de Estudios en Salud (CIESAL), Universidad de Valparaíso, Centro Asociado Cochrane Chile, Viña del Mar, ChileCentro Interdisciplinario de Estudios en Salud (CIESAL), Universidad de Valparaíso, Centro Asociado Cochrane Chile, Viña del Mar, ChileCentro Interdisciplinario de Estudios en Salud (CIESAL), Universidad de Valparaíso, Centro Asociado Cochrane Chile, Viña del Mar, ChileInstituto Universitario Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, ArgentinaThis article is part of a collaborative methodological series of narrative reviews on biostatistics and clinical epidemiology. This review aims to present basic concepts about the minimal clinically important difference and its use in the field of clinical research and evidence synthesis. The minimal clinically important difference is defined as the smallest difference in score in any domain or outcome of interest that patients can perceive as beneficial. It is a useful concept in several aspects since it links the magnitude of change with treatment decisions in clinical practice and emphasizes the primacy of the patient’s perception, affected by endless variables such as time, place, and current state of health, all of which can cause significant variability in results.https://www.medwave.cl/link.cgi/Medwave/Revisiones/MetodInvestReport/8149.actevidence-based medicineevidence-based practiceminimal clinically important differencepatient reported outcome measuressystematic reviews as topicgrade approach |
| spellingShingle | Julieta Aldana Salas Apaza Juan Víctor Ariel Franco Nicolás Meza Eva Madrid Cristobal Loézar Luis Garegnani Minimal clinically important difference: The basics Medwave evidence-based medicine evidence-based practice minimal clinically important difference patient reported outcome measures systematic reviews as topic grade approach |
| title | Minimal clinically important difference: The basics |
| title_full | Minimal clinically important difference: The basics |
| title_fullStr | Minimal clinically important difference: The basics |
| title_full_unstemmed | Minimal clinically important difference: The basics |
| title_short | Minimal clinically important difference: The basics |
| title_sort | minimal clinically important difference the basics |
| topic | evidence-based medicine evidence-based practice minimal clinically important difference patient reported outcome measures systematic reviews as topic grade approach |
| url | https://www.medwave.cl/link.cgi/Medwave/Revisiones/MetodInvestReport/8149.act |
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