Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report
Novel mRNA and vector-based covid-19 vaccinations have shown high efficacy in preventing symptomatic COVID-19 infections. Compared with the number of performed vaccinations, rates of severe side effects seem low. Rare prothrombotic coagulation disorders with suspected association to ChAdOx1 nCoV-19...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2021-07-01
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| Series: | TH Open |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1731774 |
| _version_ | 1818726138418036736 |
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| author | Martin Koch Sybille Fuld Jan M. Middeke Julia Fantana Simone von Bonin Jan Beyer-Westendorf |
| author_facet | Martin Koch Sybille Fuld Jan M. Middeke Julia Fantana Simone von Bonin Jan Beyer-Westendorf |
| author_sort | Martin Koch |
| collection | DOAJ |
| description | Novel mRNA and vector-based covid-19 vaccinations have shown high efficacy in preventing symptomatic COVID-19 infections. Compared with the number of performed vaccinations, rates of severe side effects seem low. Rare prothrombotic coagulation disorders with suspected association to ChAdOx1 nCoV-19 (AstraZeneca) have been reported. These cases have gathered considerable media attention and caused a temporary pause of usage of the AstraZeneca vaccine in Europe and several other countries and are currently discussed as vaccine-induced immune thrombotic thrombocytopenia (VITT). However, hemorrhagic complications from ChAdOx1 nCoV-19 vaccination have also been reported but, so far, received less public attention despite considerable potential for life-threatening complications. Here we present a case of severe immune thrombocytopenia after ChAdOx1 covid-19 vaccination and its successful primary management. |
| first_indexed | 2024-12-17T21:53:26Z |
| format | Article |
| id | doaj.art-3804292503c346628f451b185d84ffc3 |
| institution | Directory Open Access Journal |
| issn | 2512-9465 |
| language | English |
| last_indexed | 2024-12-17T21:53:26Z |
| publishDate | 2021-07-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | TH Open |
| spelling | doaj.art-3804292503c346628f451b185d84ffc32022-12-21T21:31:12ZengGeorg Thieme Verlag KGTH Open2512-94652021-07-010503e315e31810.1055/s-0041-1731774Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case ReportMartin Koch0Sybille Fuld1Jan M. Middeke2Julia Fantana3Simone von Bonin4Jan Beyer-Westendorf5Department of Medicine, Hematology Division, University Hospital Carl Gustav Carus, Dresden, GermanyDepartment of Medicine, Nephrology Division, University Hospital Carl Gustav Carus, Dresden, GermanyDepartment of Medicine, Hematology Division, University Hospital Carl Gustav Carus, Dresden, GermanyDepartment of Medicine, Emergency and Intensive Medicine Division, University Hospital Carl Gustav Carus, Dresden, GermanyDepartment of Medicine, Emergency and Intensive Medicine Division, University Hospital Carl Gustav Carus, Dresden, GermanyDepartment of Medicine, Hematology Division, University Hospital Carl Gustav Carus, Dresden, GermanyNovel mRNA and vector-based covid-19 vaccinations have shown high efficacy in preventing symptomatic COVID-19 infections. Compared with the number of performed vaccinations, rates of severe side effects seem low. Rare prothrombotic coagulation disorders with suspected association to ChAdOx1 nCoV-19 (AstraZeneca) have been reported. These cases have gathered considerable media attention and caused a temporary pause of usage of the AstraZeneca vaccine in Europe and several other countries and are currently discussed as vaccine-induced immune thrombotic thrombocytopenia (VITT). However, hemorrhagic complications from ChAdOx1 nCoV-19 vaccination have also been reported but, so far, received less public attention despite considerable potential for life-threatening complications. Here we present a case of severe immune thrombocytopenia after ChAdOx1 covid-19 vaccination and its successful primary management.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1731774thrombocytopeniaplatelet pathology / inheritedaquiredinfectious diseasescovid vaccinationitpitp associated with covid vaccinationitp associated with astrazeneca covid vaccinationsecondary itp |
| spellingShingle | Martin Koch Sybille Fuld Jan M. Middeke Julia Fantana Simone von Bonin Jan Beyer-Westendorf Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report TH Open thrombocytopenia platelet pathology / inherited aquired infectious diseases covid vaccination itp itp associated with covid vaccination itp associated with astrazeneca covid vaccination secondary itp |
| title | Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report |
| title_full | Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report |
| title_fullStr | Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report |
| title_full_unstemmed | Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report |
| title_short | Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report |
| title_sort | secondary immune thrombocytopenia itp associated with chadox1 covid 19 vaccination a case report |
| topic | thrombocytopenia platelet pathology / inherited aquired infectious diseases covid vaccination itp itp associated with covid vaccination itp associated with astrazeneca covid vaccination secondary itp |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1731774 |
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