Effect of troxerutin on apelin-13, apelin receptors (APJ), and ovarian histological changes in the offspring of high-fat diet fed rats

Effect of troxerutin on apelin-13, apelin receptors (APJ), and ovarian histological changes in the offspring of high-fat diet fed rats

Objective(s): Maternal high-fat diet (HFD) consumption has been linked to metabolic disorders and reproductive dysfunctions in offspring. Troxerutin (TRO) has anti-hyperlipidemic, anti-oxidant, and anti-inflammatory effects. This study examined the effects of TRO on apelin-13, its receptors mRNA and...

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Bibliographic Details
Main Authors: Keivan Mehri, Seyed Mehdi Banan Khojasteh, Fereshteh Farajdokht, Zohreh Zavvari Oskuye, Hadi Ebrahimi, Rogaye Diba, Parvin Bayandor, Maryam Hosseindoost, Shirin Babri
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Apelin-13
APJ receptor
Maternal high-fat diet
Ovarian development
Troxerutin
Online Access:http://ijbms.mums.ac.ir/article_12762_5d2c3f6bc77dc2c601ad73ea1f6f375a.pdf

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