CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPY

The article is dedicated to diagnostics and treatment of infectious complications among children with juvenile rheumatoid arthritis, receiving immunosuppressive therapy. The research involves 92 children with different variants of the illness run, who received immunosuppressive therapy. All the pati...

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Main Authors: A.M. Chomakhidze, E.I. Alexeeva, K.B. Isaeva, S.I. Valieva, T.M. Bzarova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2007-11-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/1319
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author A.M. Chomakhidze
E.I. Alexeeva
K.B. Isaeva
S.I. Valieva
T.M. Bzarova
author_facet A.M. Chomakhidze
E.I. Alexeeva
K.B. Isaeva
S.I. Valieva
T.M. Bzarova
author_sort A.M. Chomakhidze
collection DOAJ
description The article is dedicated to diagnostics and treatment of infectious complications among children with juvenile rheumatoid arthritis, receiving immunosuppressive therapy. The research involves 92 children with different variants of the illness run, who received immunosuppressive therapy. All the patients showed development of the systemic inflammatory response manifestations. The researchers used the definition of the procalcytonine levels as a marker for the bacterial infectiondevelopment. All the patients showed it higher than 0,5 ng/ml, while 7 patients — higher than 10 ng/ml. keeping in mind several courses of the antibacterial therapy in the anamnesis and presence of the combined bacterial infection, ceftriaxone was prescribed to all the children. As a result of the ceftriaxone based therapy, reduction of the clinical and laboratory manifestations of the bacterial infection was noted among more than 90% of patients. The development of the allergic reaction was noted in 1 case, and leukopenia was also found in 1 patient.Key words: children, juvenile rheumatoid arthritis, ceftriaxone.
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spelling doaj.art-380b7ba747bf4b1caeb56c8c71f597122025-03-02T11:34:15Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352007-11-0166951001319CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPYA.M. Chomakhidze0E.I. Alexeeva1K.B. Isaeva2S.I. Valieva3T.M. Bzarova4Scientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowThe article is dedicated to diagnostics and treatment of infectious complications among children with juvenile rheumatoid arthritis, receiving immunosuppressive therapy. The research involves 92 children with different variants of the illness run, who received immunosuppressive therapy. All the patients showed development of the systemic inflammatory response manifestations. The researchers used the definition of the procalcytonine levels as a marker for the bacterial infectiondevelopment. All the patients showed it higher than 0,5 ng/ml, while 7 patients — higher than 10 ng/ml. keeping in mind several courses of the antibacterial therapy in the anamnesis and presence of the combined bacterial infection, ceftriaxone was prescribed to all the children. As a result of the ceftriaxone based therapy, reduction of the clinical and laboratory manifestations of the bacterial infection was noted among more than 90% of patients. The development of the allergic reaction was noted in 1 case, and leukopenia was also found in 1 patient.Key words: children, juvenile rheumatoid arthritis, ceftriaxone.https://vsp.spr-journal.ru/jour/article/view/1319
spellingShingle A.M. Chomakhidze
E.I. Alexeeva
K.B. Isaeva
S.I. Valieva
T.M. Bzarova
CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPY
Вопросы современной педиатрии
title CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPY
title_full CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPY
title_fullStr CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPY
title_full_unstemmed CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPY
title_short CEFTRIAXONE EFFICIENCY AMONG PATIENTS, SUFFERING FROM JUVENILE ARTHRITIS AND RECEIVING IMMUNOSUPPRESSIVE THERAPY
title_sort ceftriaxone efficiency among patients suffering from juvenile arthritis and receiving immunosuppressive therapy
url https://vsp.spr-journal.ru/jour/article/view/1319
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