Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of Scabies
Background: Scabies is a contagious pruritic skin condition caused by the mite Sarcoptesscabiei var. hominis, and it is one of the major public health problem in developing country like ours. To determine and compare the efficacy of topical permethrin and topical gamma benzene hexachloride in treatm...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nobel Medical College Teaching Hospital
2018-12-01
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| Series: | Journal of Nobel Medical College |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/JoNMC/article/view/22307 |
| _version_ | 1819087778713960448 |
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| author | Manish Pradhan Dipa Rai Sagar Paudel Chandra Bhal Jha |
| author_facet | Manish Pradhan Dipa Rai Sagar Paudel Chandra Bhal Jha |
| author_sort | Manish Pradhan |
| collection | DOAJ |
| description | Background: Scabies is a contagious pruritic skin condition caused by the mite Sarcoptesscabiei var. hominis, and it is one of the major public health problem in developing country like ours. To determine and compare the efficacy of topical permethrin and topical gamma benzene hexachloride in treatment of scabies in population of Nepal.
Methods: This was a prospective, randomized, comparative study conducted in 300 diagnosed cases of scabies treated with permethrin and gamma benzene hexachloride.
Results: At the end of 2nd week, treatment was effective in 91.2% cases in permethrin (group A) and 64.6% in gamma benzene hexachloride (group B). After switch over of the non-improved patients to the other group drug, 6.7% were treated successfully with gamma benzene hexachloride and 80.9% were treated successfully with permethrin at the end of 4th week. No major side effects were observed in both groups. Gamma benzene hexachloride was found to be cost effective than permethrin.
Conclusion: Permethrin was found to be more effective than gamma benzene hexachloride in treatment of scabies. |
| first_indexed | 2024-12-21T21:41:33Z |
| format | Article |
| id | doaj.art-380ef9d9b1d34fb19021e31debc389ec |
| institution | Directory Open Access Journal |
| issn | 2091-2331 2091-234X |
| language | English |
| last_indexed | 2024-12-21T21:41:33Z |
| publishDate | 2018-12-01 |
| publisher | Nobel Medical College Teaching Hospital |
| record_format | Article |
| series | Journal of Nobel Medical College |
| spelling | doaj.art-380ef9d9b1d34fb19021e31debc389ec2022-12-21T18:49:20ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2018-12-0172444910.3126/jonmc.v7i2.2230722307Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of ScabiesManish Pradhan0Dipa Rai1Sagar Paudel2Chandra Bhal Jha3Department of Dermatology, Nobel Medical College Teaching HospitalDepartment of Dermatology, Nobel Medical College Teaching HospitalDepartment of Dermatology, Nobel Medical College Teaching HospitalDepartment of Dermatology, Mechi Zonal HospitalBackground: Scabies is a contagious pruritic skin condition caused by the mite Sarcoptesscabiei var. hominis, and it is one of the major public health problem in developing country like ours. To determine and compare the efficacy of topical permethrin and topical gamma benzene hexachloride in treatment of scabies in population of Nepal. Methods: This was a prospective, randomized, comparative study conducted in 300 diagnosed cases of scabies treated with permethrin and gamma benzene hexachloride. Results: At the end of 2nd week, treatment was effective in 91.2% cases in permethrin (group A) and 64.6% in gamma benzene hexachloride (group B). After switch over of the non-improved patients to the other group drug, 6.7% were treated successfully with gamma benzene hexachloride and 80.9% were treated successfully with permethrin at the end of 4th week. No major side effects were observed in both groups. Gamma benzene hexachloride was found to be cost effective than permethrin. Conclusion: Permethrin was found to be more effective than gamma benzene hexachloride in treatment of scabies.https://www.nepjol.info/index.php/JoNMC/article/view/22307gammabenzenehexachloridepermethrinscabies |
| spellingShingle | Manish Pradhan Dipa Rai Sagar Paudel Chandra Bhal Jha Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of Scabies Journal of Nobel Medical College gammabenzenehexachloride permethrin scabies |
| title | Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of Scabies |
| title_full | Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of Scabies |
| title_fullStr | Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of Scabies |
| title_full_unstemmed | Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of Scabies |
| title_short | Comparative Trials of 5% Permethrin Lotions Vs 1% Gamma Benzene Hexachloride Lotions in Treatment of Scabies |
| title_sort | comparative trials of 5 permethrin lotions vs 1 gamma benzene hexachloride lotions in treatment of scabies |
| topic | gammabenzenehexachloride permethrin scabies |
| url | https://www.nepjol.info/index.php/JoNMC/article/view/22307 |
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