Sex Differences in the Hepatic Cholesterol Sensing Mechanisms in Mice

Sex Differences in the Hepatic Cholesterol Sensing Mechanisms in Mice

Cholesterol is linked to many multifactorial disorders, including different forms of liver disease where development and severity depend on the sex. We performed a detailed analysis of cholesterol and bile acid synthesis pathways at the level of genes and metabolites combined with the expression stu...

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Bibliographic Details
Main Authors: Ingemar Björkhem, Damjana Rozman, Simon Horvat, Martina Perše, Gregor Lorbek
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Molecules
Subjects:
cholesterol synthesis
high-fat diet
gene expression
sterol
bile acid
liver
mouse
Online Access:http://www.mdpi.com/1420-3049/18/9/11067

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