Electroanalysis of Fentanyl and Its New Analogs: A Review

The review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The...

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Main Authors: Marta Katarzyna Choińska, Ivana Šestáková, Vojtěch Hrdlička, Jana Skopalová, Jan Langmaier, Vítězslav Maier, Tomáš Navrátil
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/12/1/26
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author Marta Katarzyna Choińska
Ivana Šestáková
Vojtěch Hrdlička
Jana Skopalová
Jan Langmaier
Vítězslav Maier
Tomáš Navrátil
author_facet Marta Katarzyna Choińska
Ivana Šestáková
Vojtěch Hrdlička
Jana Skopalová
Jan Langmaier
Vítězslav Maier
Tomáš Navrátil
author_sort Marta Katarzyna Choińska
collection DOAJ
description The review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The review also covers the analysis of new synthetic opioids, their parent compounds, and corresponding metabolites in body fluids, such as urine, blood, serum, and plasma, necessary for a fast and accurate diagnosis of intoxication. Identifying and quantifying these addictive and illicit substances and their metabolites is necessary for clinical, toxicological, and forensic purposes. As a reaction to the growing number of new synthetic opioid intoxications and increasing fatalities observed over the past ten years, we provide thorough background for developing new biosensors, screen-printed electrodes, or other point-of-care devices.
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spelling doaj.art-38199c9e192b46bfb5a7ebd613f703702023-11-23T13:08:10ZengMDPI AGBiosensors2079-63742022-01-011212610.3390/bios12010026Electroanalysis of Fentanyl and Its New Analogs: A ReviewMarta Katarzyna Choińska0Ivana Šestáková1Vojtěch Hrdlička2Jana Skopalová3Jan Langmaier4Vítězslav Maier5Tomáš Navrátil6J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicDepartment of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. Listopadu 12, 771 46 Olomouc, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicDepartment of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. Listopadu 12, 771 46 Olomouc, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicThe review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The review also covers the analysis of new synthetic opioids, their parent compounds, and corresponding metabolites in body fluids, such as urine, blood, serum, and plasma, necessary for a fast and accurate diagnosis of intoxication. Identifying and quantifying these addictive and illicit substances and their metabolites is necessary for clinical, toxicological, and forensic purposes. As a reaction to the growing number of new synthetic opioid intoxications and increasing fatalities observed over the past ten years, we provide thorough background for developing new biosensors, screen-printed electrodes, or other point-of-care devices.https://www.mdpi.com/2079-6374/12/1/26fentanylfentanyl analogsamperometryvoltammetryscreen-printed electrodemetabolite
spellingShingle Marta Katarzyna Choińska
Ivana Šestáková
Vojtěch Hrdlička
Jana Skopalová
Jan Langmaier
Vítězslav Maier
Tomáš Navrátil
Electroanalysis of Fentanyl and Its New Analogs: A Review
Biosensors
fentanyl
fentanyl analogs
amperometry
voltammetry
screen-printed electrode
metabolite
title Electroanalysis of Fentanyl and Its New Analogs: A Review
title_full Electroanalysis of Fentanyl and Its New Analogs: A Review
title_fullStr Electroanalysis of Fentanyl and Its New Analogs: A Review
title_full_unstemmed Electroanalysis of Fentanyl and Its New Analogs: A Review
title_short Electroanalysis of Fentanyl and Its New Analogs: A Review
title_sort electroanalysis of fentanyl and its new analogs a review
topic fentanyl
fentanyl analogs
amperometry
voltammetry
screen-printed electrode
metabolite
url https://www.mdpi.com/2079-6374/12/1/26
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