Electroanalysis of Fentanyl and Its New Analogs: A Review
The review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The...
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Format: | Article |
Language: | English |
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MDPI AG
2022-01-01
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Series: | Biosensors |
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Online Access: | https://www.mdpi.com/2079-6374/12/1/26 |
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author | Marta Katarzyna Choińska Ivana Šestáková Vojtěch Hrdlička Jana Skopalová Jan Langmaier Vítězslav Maier Tomáš Navrátil |
author_facet | Marta Katarzyna Choińska Ivana Šestáková Vojtěch Hrdlička Jana Skopalová Jan Langmaier Vítězslav Maier Tomáš Navrátil |
author_sort | Marta Katarzyna Choińska |
collection | DOAJ |
description | The review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The review also covers the analysis of new synthetic opioids, their parent compounds, and corresponding metabolites in body fluids, such as urine, blood, serum, and plasma, necessary for a fast and accurate diagnosis of intoxication. Identifying and quantifying these addictive and illicit substances and their metabolites is necessary for clinical, toxicological, and forensic purposes. As a reaction to the growing number of new synthetic opioid intoxications and increasing fatalities observed over the past ten years, we provide thorough background for developing new biosensors, screen-printed electrodes, or other point-of-care devices. |
first_indexed | 2024-03-10T01:48:52Z |
format | Article |
id | doaj.art-38199c9e192b46bfb5a7ebd613f70370 |
institution | Directory Open Access Journal |
issn | 2079-6374 |
language | English |
last_indexed | 2024-03-10T01:48:52Z |
publishDate | 2022-01-01 |
publisher | MDPI AG |
record_format | Article |
series | Biosensors |
spelling | doaj.art-38199c9e192b46bfb5a7ebd613f703702023-11-23T13:08:10ZengMDPI AGBiosensors2079-63742022-01-011212610.3390/bios12010026Electroanalysis of Fentanyl and Its New Analogs: A ReviewMarta Katarzyna Choińska0Ivana Šestáková1Vojtěch Hrdlička2Jana Skopalová3Jan Langmaier4Vítězslav Maier5Tomáš Navrátil6J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicDepartment of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. Listopadu 12, 771 46 Olomouc, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicDepartment of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. Listopadu 12, 771 46 Olomouc, Czech RepublicJ. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23 Prague, Czech RepublicThe review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The review also covers the analysis of new synthetic opioids, their parent compounds, and corresponding metabolites in body fluids, such as urine, blood, serum, and plasma, necessary for a fast and accurate diagnosis of intoxication. Identifying and quantifying these addictive and illicit substances and their metabolites is necessary for clinical, toxicological, and forensic purposes. As a reaction to the growing number of new synthetic opioid intoxications and increasing fatalities observed over the past ten years, we provide thorough background for developing new biosensors, screen-printed electrodes, or other point-of-care devices.https://www.mdpi.com/2079-6374/12/1/26fentanylfentanyl analogsamperometryvoltammetryscreen-printed electrodemetabolite |
spellingShingle | Marta Katarzyna Choińska Ivana Šestáková Vojtěch Hrdlička Jana Skopalová Jan Langmaier Vítězslav Maier Tomáš Navrátil Electroanalysis of Fentanyl and Its New Analogs: A Review Biosensors fentanyl fentanyl analogs amperometry voltammetry screen-printed electrode metabolite |
title | Electroanalysis of Fentanyl and Its New Analogs: A Review |
title_full | Electroanalysis of Fentanyl and Its New Analogs: A Review |
title_fullStr | Electroanalysis of Fentanyl and Its New Analogs: A Review |
title_full_unstemmed | Electroanalysis of Fentanyl and Its New Analogs: A Review |
title_short | Electroanalysis of Fentanyl and Its New Analogs: A Review |
title_sort | electroanalysis of fentanyl and its new analogs a review |
topic | fentanyl fentanyl analogs amperometry voltammetry screen-printed electrode metabolite |
url | https://www.mdpi.com/2079-6374/12/1/26 |
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