Mechanistic Insight into the Enzymatic Inhibition of β-Amyrin against Mycobacterial Rv1636: In Silico and In Vitro Approaches

Mechanistic Insight into the Enzymatic Inhibition of β-Amyrin against Mycobacterial Rv1636: In Silico and In Vitro Approaches

<i>Mycobacterium tuberculosis</i> has seen tremendous success as it has developed defenses to reside in host alveoli despite various host-related stress circumstances. Rv1636 is a universal stress protein contributing to mycobacterial survival in different host-derived stress conditions....

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Bibliographic Details
Main Authors: Md Amjad Beg, Sadaf, Anas Shamsi, Sibasis Sahoo, Mohd Yousuf, Mohammad Zeeshan Najm, Yahya Ahmad Almutawif, Asimul Islam, Abdulaziz A. Aloliqi, Fareeda Athar
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biology
Subjects:
Rv1636
β-Amyrin
molecular docking
molecular dynamics simulation
circular dichroism spectroscopy
isothermal titration calorimetry
Online Access:https://www.mdpi.com/2079-7737/11/8/1214

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