Sedentary Behavior Impacts on the Epigenome and Transcriptome: Lessons from Muscle Inactivation in <i>Drosophila</i> Larvae

Sedentary Behavior Impacts on the Epigenome and Transcriptome: Lessons from Muscle Inactivation in <i>Drosophila</i> Larvae

The biological mechanisms linking sedentary lifestyles and metabolic derangements are incompletely understood. In this study, temporal muscle inactivation in <i>Drosophila</i> larvae carrying a temperature-sensitive mutation in the <i>shibire</i> (<i>shi<sup>1<...

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Bibliographic Details
Main Authors: Avivit Brener, Dana Lorber, Adriana Reuveny, Hila Toledano, Lilach Porat-Kuperstein, Yael Lebenthal, Eviatar Weizman, Tsviya Olender, Talila Volk
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
aging
epigenetics
lncRNA
proteostasis
sarcopenia
ubiquitination
Online Access:https://www.mdpi.com/2073-4409/12/19/2333

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