Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study

Adrenaline auto injectors (AAI) are the mainstay of treatment in anaphylaxis. However, many caregivers of children with food allergies are unable to administer an AAI when assessed. One proposed factor for this finding is the lack of training and familiarity of the different AAI devices. The aim of...

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Main Authors: Caoimhe Cronin, Ciobha O’Kelly, Hannah Keohane, Laura Flores Villarta, Ciara Tobin, Roberto Velasco, Juan Trujillo Wurttele
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Allergies
Subjects:
Online Access:https://www.mdpi.com/2313-5786/3/2/8
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author Caoimhe Cronin
Ciobha O’Kelly
Hannah Keohane
Laura Flores Villarta
Ciara Tobin
Roberto Velasco
Juan Trujillo Wurttele
author_facet Caoimhe Cronin
Ciobha O’Kelly
Hannah Keohane
Laura Flores Villarta
Ciara Tobin
Roberto Velasco
Juan Trujillo Wurttele
author_sort Caoimhe Cronin
collection DOAJ
description Adrenaline auto injectors (AAI) are the mainstay of treatment in anaphylaxis. However, many caregivers of children with food allergies are unable to administer an AAI when assessed. One proposed factor for this finding is the lack of training and familiarity of the different AAI devices. The aim of this study is to explore the usage of different brands of adrenaline auto-injectors among caregivers of children with food allergies in Ireland. A cross-sectional study method was employed using an online questionnaire. An amount of 121 (75.58%) caregivers reported that their child carried an Epipen<sup>®</sup>, 25 (15.82%) carried Jext<sup>®</sup>, and 12 (7.59%) carried Anapen<sup>®</sup>. An amount of 48.73% (n = 77) of caregivers had switched brands of AAI at least once before, with lack of availability of their usual device at their pharmacy being the most common reason for this. Factors associated with change were a household income >100,000 € (70% vs. 44.9% of those with less income; <i>p</i> = 0.04) and parents ≥40 years old (59.6% vs. 32.8% of patients whose parents younger; <i>p</i> < 0.01). When asked what they preferred about a particular AAI brand, caregivers appreciated a simple design with minimal steps involved in administration, clear colour coding, online resources, formal training from a healthcare professional, and first-hand experience in using the AAI. These findings show, for the first time, that switching brands is a common occurrence among caregivers of children with food allergies. These findings support the EAACI recommendation to train parents regularly in all available brands of AAI and to retrain parents when switching to different devices.
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spelling doaj.art-381c55b5bb8b4d19b7fe930a77968b982023-11-18T08:57:07ZengMDPI AGAllergies2313-57862023-05-013210511410.3390/allergies3020008Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional StudyCaoimhe Cronin0Ciobha O’Kelly1Hannah Keohane2Laura Flores Villarta3Ciara Tobin4Roberto Velasco5Juan Trujillo Wurttele6Department of Paediatrics and Child Health, University College Cork, T12 DC4A Cork, IrelandHRB Clinical Research Facility Cork (CRF-C), Irish Centre for Maternal and Child Health Research (INFANT), Cork University Hospital, T12 DC4A Cork, IrelandDepartment of Paediatrics and Child Health, University College Cork, T12 DC4A Cork, IrelandDepartment of Paediatrics and Child Health, University College Cork, T12 DC4A Cork, IrelandHRB Clinical Research Facility Cork (CRF-C), Irish Centre for Maternal and Child Health Research (INFANT), Cork University Hospital, T12 DC4A Cork, IrelandGerencia de Atención Primaria Valladolid Este, 54, 47010 Valladolid, SpainDepartment of Paediatrics and Child Health, University College Cork, T12 DC4A Cork, IrelandAdrenaline auto injectors (AAI) are the mainstay of treatment in anaphylaxis. However, many caregivers of children with food allergies are unable to administer an AAI when assessed. One proposed factor for this finding is the lack of training and familiarity of the different AAI devices. The aim of this study is to explore the usage of different brands of adrenaline auto-injectors among caregivers of children with food allergies in Ireland. A cross-sectional study method was employed using an online questionnaire. An amount of 121 (75.58%) caregivers reported that their child carried an Epipen<sup>®</sup>, 25 (15.82%) carried Jext<sup>®</sup>, and 12 (7.59%) carried Anapen<sup>®</sup>. An amount of 48.73% (n = 77) of caregivers had switched brands of AAI at least once before, with lack of availability of their usual device at their pharmacy being the most common reason for this. Factors associated with change were a household income >100,000 € (70% vs. 44.9% of those with less income; <i>p</i> = 0.04) and parents ≥40 years old (59.6% vs. 32.8% of patients whose parents younger; <i>p</i> < 0.01). When asked what they preferred about a particular AAI brand, caregivers appreciated a simple design with minimal steps involved in administration, clear colour coding, online resources, formal training from a healthcare professional, and first-hand experience in using the AAI. These findings show, for the first time, that switching brands is a common occurrence among caregivers of children with food allergies. These findings support the EAACI recommendation to train parents regularly in all available brands of AAI and to retrain parents when switching to different devices.https://www.mdpi.com/2313-5786/3/2/8anaphylaxisadrenaline auto injectorcaregiversallergychildren
spellingShingle Caoimhe Cronin
Ciobha O’Kelly
Hannah Keohane
Laura Flores Villarta
Ciara Tobin
Roberto Velasco
Juan Trujillo Wurttele
Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study
Allergies
anaphylaxis
adrenaline auto injector
caregivers
allergy
children
title Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study
title_full Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study
title_fullStr Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study
title_full_unstemmed Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study
title_short Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study
title_sort is switching of adrenaline auto injector devices a concern for anaphylaxis management a cross sectional study
topic anaphylaxis
adrenaline auto injector
caregivers
allergy
children
url https://www.mdpi.com/2313-5786/3/2/8
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AT hannahkeohane isswitchingofadrenalineautoinjectordevicesaconcernforanaphylaxismanagementacrosssectionalstudy
AT laurafloresvillarta isswitchingofadrenalineautoinjectordevicesaconcernforanaphylaxismanagementacrosssectionalstudy
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